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The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.

Flutamide reduces hair growth better but has more side effects.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Finasteride improves acne and hair loss in women with normal testosterone.

Mice with human gene experienced hair loss when treated with DHT.

Quercetin may help with PCOS symptoms, but more research is needed.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Raspberry ketone may help grow hair and improve skin elasticity.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Signaling pathways are crucial for hair growth in goats.

Men with testicular cancer were less likely to experience baldness and severe acne.

The study concluded that both anti-Mullerian hormone and LH/FSH ratio are higher in women with PCOS and combining these markers with BMI could improve diagnosis accuracy.