Metabolic Syndrome and Metabolic Risk Profile According to Polycystic Ovary Syndrome Phenotype

    April 2016 in “ Journal of Obstetrics and Gynaecology Research ”
    Enes Bil, Berna Dilbaz, Derya Akdağ Cırık, Runa Ozelci, Enis Ozkaya, Serdar Dilbaz
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    TLDR Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.
    The study assessed the relationship between different polycystic ovary syndrome (PCOS) phenotypes and the risk of metabolic syndrome (MetS) in 100 newly diagnosed PCOS women. It found that MetS was significantly more prevalent in the more severe PCOS phenotypes A (29.6%) and B (34.5%) compared to the milder phenotypes C (10.0%) and D (8.3%). Additionally, the visceral adiposity index (VAI) was identified as the only independent predictor of MetS across PCOS phenotypes, with a notably higher VAI in phenotype B. The research concluded that PCOS phenotypes A and B are at a higher risk for MetS and that VAI could be a valuable predictor of metabolic risk in PCOS women. However, the study's limitations include its cross-sectional design and the small sample size, indicating a need for larger, multi-center studies with longer follow-up to confirm the predictive value of VAI.
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