research The Human Tri-Peptide GHK and Tissue Remodeling
The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
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570-600 / 1000+ results research The Pathobiology of Skin Aging
The document reviewed the complex phenomenon of skin aging, identifying it as a degenerative disease influenced by intrinsic and environmental factors, leading to issues like atrophy, fragility, defective repair, and reduced immunity. It highlighted the roles of stem cell dysfunction and genetic and epigenetic factors in skin aging, which also affected the microbiome and cancer development. Key changes in aged skin included altered keratinocyte and melanocyte distribution, reduced collagen and elastin, fibroblast structural changes, and increased matrix metalloproteinases, contributing to collagen breakdown. Aged skin also showed reduced immune function and increased susceptibility to infections. The review emphasized the need for future research to develop strategies to mitigate skin aging effects and improve public health strategies.
research Hardwiring Stem Cell Communication Through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research Electrospun Nanofibers for Improved Angiogenesis: Promises for Tissue Engineering Applications
Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know?
Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
research Regulation of the Wound Healing Response During Aging
Aging slows wound healing due to weaker cells and immune response.
research Live Imaging of Stem Cells: Answering Old Questions and Raising New Ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Wound Healing in Development: Mechanisms and Regulation
Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
research Stem Cells Behind the Barrier: Mechanisms Regulating Epidermal Stem and Progenitor Cell Differentiation
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Activation of mTORC1 Signaling Is Required for Timely Hair Follicle Regeneration from Radiation Injury
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
research Skin Tissue Engineering: Potential of Stem Cell Biology and Skin Morphogenesis
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Clonal Analysis of Stem Cells in Differentiation and Disease
New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research A Novel Antibacterial Hydrogel Based on Thiolated Ovalbumin/Gelatin with Silver Ions to Promote Wound Healing in Mice
The new hydrogel with silver helps wounds heal faster and better in mice.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research MG53 Mitigates Nitrogen Mustard-Induced Skin Injury
MG53 helps reduce skin damage caused by nitrogen mustard.
research Sustained Release of EGF/bFGF Growth Factors by Mussel-Inspired Core-Shell Nanofibers with Hemostatic and Anti-Inflammatory Effects for Promoting Wound Healing
The new nanofiber improves wound healing by releasing growth factors, reducing inflammation, and helping skin regeneration.
research Food-Derived Crassostrea Gigas Peptides Self-Assembled Supramolecules for Scarless Healing
Pacific oyster peptides may help wounds heal without scars.
research Pharmacological Application of Growth Factors: Basic and Clinical
Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.
research Intraoperative Bioprinting of Human Adipose-Derived Stem Cells and Extracellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation During Full-Thickness Craniomaxillofacial Skin Reconstruction
Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.
research Nanomaterials Applied in Wound Healing: Mechanisms, Limitations, and Perspectives
Nanomaterials can significantly improve wound healing and future treatments may include smart, real-time monitoring.
research Scalp Rupture-Related Acute Hair Matting in a Child: A Case Report
Scalp injuries and harsh hair care can cause severe hair matting in children.
research Facile Strategy for Gelatin-Based Hydrogel with Multifunctionalities to Remodel Wound Microenvironment and Accelerate Healing of Acute and Diabetic Wounds
The gelatin-based hydrogel helps heal acute and diabetic wounds faster by improving healing conditions.
research Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research Men's Skin Needs Energy for Proper Skin Recovery and the Combination of Compounds A and B Exhibits Strong Antioxidant and Energy-Amplifying Benefits
Compounds A and B help men's skin recover faster by reducing oxidative damage and increasing energy levels.
research Lef1 Expression in Fibroblasts Maintains Developmental Potential in Adult Skin to Regenerate Wounds
Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.
research A New Scalp Treatment for Anti-Aging Hair
The new scalp treatment preserves hair color, reduces hair loss, and maintains hair strength.
research Sirtuins Pathways and Redox Homeostasis: A Pilot Study on Young and Old Monozygotic Twins
The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.
research Hair Loss in a Female Distance Runner
A female runner's hair loss was caused by stress from surgery and recovery, but her hair returned to normal in 5 months.