41 citations,
December 2015 in “JAMA Dermatology” Tofacitinib citrate improved nail dystrophy and pain in patients with alopecia universalis without causing side effects.
40 citations,
July 2015 in “Kidney International” IL-3 worsens lupus nephritis and blocking it improves kidney health.
38 citations,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
37 citations,
April 1979 in “The Journal of Clinical Pharmacology” Minoxidil effectively controls blood pressure but side effects may limit its use.
36 citations,
June 2003 in “The journal of small animal practice/Journal of small animal practice” Trilostane helped a cat with a hormone issue but the cat later died from a kidney infection.
35 citations,
May 2008 in “Journal of Clinical Oncology” A cancer patient died from a severe skin reaction after taking the drug cetuximab.
34 citations,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
34 citations,
June 2005 in “Journal of cosmetic dermatology” Medium-depth peels are safer and effective for improving skin appearance compared to deep peels.
33 citations,
January 2011 in “Elsevier eBooks” Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
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January 2006 in “Liver transplantation” Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
31 citations,
August 2018 in “Journal of biomedical nanotechnology” Licorice root-derived nanoparticles target liver cancer cells to improve treatment and reduce side effects.
26 citations,
May 2000 in “Journal of The American Academy of Dermatology” Finasteride improves hair growth.
25 citations,
June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
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July 2015 in “Encyclopedia of Life Sciences” Systemic lupus erythematosus is a chronic disease causing inflammation and various symptoms, mainly in young women, treated with anti-inflammatory and immunosuppressive drugs.
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August 1987 in “Archives of Dermatology” High-dose methotrexate can cause severe skin and nail issues.
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January 2019 in “Toxicology Reports” Dunaliella salina microalgae is safe to eat and may boost health.
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March 2018 in “Expert Opinion on Drug Safety” Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.
16 citations,
March 2011 in “Ophthalmic genetics” A patient with Birt-Hogg-Dubé Syndrome also had choroidal melanoma, suggesting the need for careful eyelid exams in such patients.
15 citations,
December 2014 in “Dermatology and therapy” Sorafenib can cause facial acne-like eruptions, which improve after reducing the dose or stopping the drug.
13 citations,
July 1978 in “Journal of comparative pathology” Acanthospermum hispidum is toxic to mice, causing death and damage to internal organs.
12 citations,
January 2014 in “Journal of international medical research” Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.
12 citations,
January 2011 in “Dermatologic Surgery” Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.
11 citations,
August 2012 in “BMJ case reports” Ban Tu Wan, a Chinese herbal supplement, can cause severe liver damage.
8 citations,
January 2013 in “Medicinal chemistry” The compound 4c showed strong potential as an anticancer agent.
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March 2019 in “Journal of The European Academy of Dermatology and Venereology” A man developed a skin reaction from metronidazole, which improved after stopping the drug and starting steroids.
6 citations,
February 2021 in “Frontiers in Neurology” Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.
6 citations,
January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil can be effective for hair loss but should be avoided in people with certain heart conditions and severe liver problems.
6 citations,
November 2018 in “Case reports in nephrology and dialysis” Rituximab may be an effective treatment for Cronkhite-Canada syndrome with kidney disease.
6 citations,
May 1986 in “Cancer Chemotherapy and Pharmacology” The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.
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June 2015 in “Chinese journal of natural medicines/Zhongguo tianran yaowu/Chinese Journal of Natural Medicines” Tripterygium wilfordii multiglycoside effectively reduced prostate enlargement in rats without harmful effects.