TLDR Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
In a study from 1982 involving 126 patients with hypertension resistant to conventional treatment, various regimens were assessed, including oral diazoxide, minoxidil, captopril, and quadruple therapy. The study found that blood pressure could be controlled in nearly all patients, with no deaths from cerebrovascular disease during treatment. However, 2 patients died from renal failure, 5 required long-term haemodialysis, and ischaemic heart disease caused 10 deaths. Diazoxide was the most effective in controlling blood pressure but was also the most difficult and unpleasant to use. Captopril was well-tolerated but failed in 6 out of 15 patients. The study concluded that while no treatment is perfect, there are now enough alternatives to manage blood pressure in patients with refractory hypertension effectively.
16 citations,
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26 citations,
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January 2023 in “Dermatologic Therapy” The new 5% minoxidil foam is as effective and safe as Rogaine® for treating hair loss in Chinese men.
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January 1995 in “Skin Pharmacology and Physiology” SEPA™ enhances the effectiveness of minoxidil in stimulating hair growth, working faster and better than Rogaine® TS, with no significant side effects.
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May 2014 in “Hair transplant forum international” Rogaine can stop hair loss in women, and other treatments like certain pills, light therapy, and special shampoos may also work.
April 2011 in “The FASEB Journal” Topical Minoxidil is cost-effective for managing baldness but requires continuous use.
January 2011 in “The Internet Journal of Pharmacology” Minoxidil is cost-effective for regrowing hair on the scalp's top but not the front, requiring ongoing use.
