Vitamin A Toxicity: When One a Day Doesn't Keep the Doctor Away

    January 2006 in “ Liver transplantation ”
    Rekha Cheruvattath, Mauricio Orrego, Mamta Gautam, Thomas Byrne, Shayan Alam, Marina Voltchenok, Mark Edwin, James A. Wilkens, James W. Williams, Hugo E. Vargas
    TLDR Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
    The document reported a case of a 60-year-old man who developed severe liver injury due to subacute vitamin A toxicity, leading to liver transplantation. The patient had been consuming excessive amounts of vitamin A, far exceeding the recommended daily value, which resulted in symptoms such as muscle soreness, hair loss, skin rash, and nail dystrophy. Despite discontinuing the supplements, his condition worsened, leading to refractory ascites, severe encephalopathy, and renal failure. A liver biopsy revealed significant liver damage compatible with hypervitaminosis A. The patient underwent a successful liver transplant and made a remarkable recovery. This case highlighted the potential severity of vitamin A toxicity and suggested that liver transplantation could be a viable option when hepatic decompensation occurs despite stopping the toxic medication.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community 3yr Fin/Dut/Niz NW3+ —> NW1.5 Pictures with Writeup

      in Progress Pictures  31 upvotes 4 years ago
      A user improved their hair loss from NW3+ to NW1.5 over three years using a regimen of dutasteride, finasteride, Nizoral, biotin, and collagen. They experienced some side effects and adjusted dosages over time, and noted additional benefits like better skin and muscle gain.

      community Going to try and reverse MPB naturally.

      in Treatment  55 upvotes 2 years ago
      A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.

      community 25 Years old. 3 Months on Fin/Min, plus Hair & Nail Vitamins.

      in Progress Pictures  379 upvotes 1 year ago
      The conclusion of the conversation is that the user, Lead_Tasso, is expressing gratitude for the community's help in restoring their confidence in treating hair loss. They have been using finasteride (fin) and minoxidil (min) and have also been taking hair and nail vitamins.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  738 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

    Similar Research

    5 / 1000+ results