21 citations
,
November 2017 in “Archives of Dermatological Research” This study found that women with female pattern hair loss had increased 5α-reductase isozymes and decreased aromatase mRNA levels, potentially affecting their response to treatment.
21 citations
,
February 2017 in “International Journal of Women's Dermatology” This review discusses the physiology and potential hormonal mechanisms involved in female pattern hair loss, as well as the current hormonal and hormone-modifying treatments available, but reports no new research findings.
21 citations
,
May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
20 citations
,
September 2021 in “Nature communications” In this study, researchers identified a gene expression pre-pattern and implicated the Wnt inhibitor Dickkopf 4 in the formation of color patterns in domestic cat embryos.
20 citations
,
August 2016 in “International Journal of Cancer” This study reports that male-pattern baldness may be linked to an increased risk of skin cancer, particularly for tumors located on the scalp.
19 citations
,
April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
19 citations
,
February 2008 in “Archives of Dermatological Research” This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.
15 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article reviews pharmacologic treatments for pattern hair loss and emphasizes integrating them with surgical and nonmedical options, but it does not present new clinical findings.
14 citations
,
January 2016 in “Experimental Dermatology” This analysis concluded that hair regrowth in male and female pattern hair loss treatments did not involve converting vellus hairs into terminal hairs, suggesting a reactivation of dormant non-vellus follicles instead.
13 citations
,
January 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This abstract discusses platelet-rich plasma therapy for patterned hair loss but provides no new clinical results, suggesting further research is needed to determine its effectiveness.
12 citations
,
November 2019 in “PLoS ONE” This study suggests a weak association between male-pattern baldness and some coronary heart disease risk factors, but does not support it as a strong indicator of coronary risk.
10 citations
,
September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
10 citations
,
January 2010 in “PubMed” This article reviews current hair loss treatments, proposing a hypothesis that a combination of drugs, supplements, and therapies may effectively manage hair loss, but presents no new clinical results.
8 citations
,
May 2024 in “PLoS Biology” This study on feather pattern formation in chicken skin found that inhibiting gap junctional intercellular communication can lead to the emergence of new feather buds in specific spatial patterns, suggesting that GJIC may facilitate Turing-type periodic patterning by propagating inhibitory signals over long distances.
8 citations
,
January 2013 in “BioMed Research International” This study observed that both Factor XIIIa+ dermal dendrocytes and microvasculature size decreased with scalp aging and that alopecia changes resembled stress-induced premature senescence.
7 citations
,
October 2022 in “Advances in Therapy” This review of real-world treatment options for AA indicates that current therapies are insufficient, with high dissatisfaction rates, highlighting a need for improved solutions.
7 citations
,
May 2019 in “Journal of the Formosan Medical Association” This study found that overweight women with polycystic ovary syndrome carrying the HSD3B1 1245C allele had an increased presence of female pattern hair loss compared to those with the wild-type genotype.
7 citations
,
March 2019 in “Medicine” This protocol outlines a study aiming to determine if combining 660 nm red laser photobiomodulation and microneedling increases hair density in female pattern hair loss, but it reports no results yet.
6 citations
,
April 2017 in “Journal of Dermatological Science” This study aimed to evaluate the potential use of ovariectomized mice as a model for postmenopausal female pattern hair loss, but it reports no new results.
5 citations
,
October 2020 in “Lasers in Medical Science” This study found that combination therapy with LLLT and 5% minoxidil improved hair diameter and density more effectively than each treatment alone in women with female pattern hair loss.
5 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.
5 citations
,
November 1999 in “Medical Hypotheses” Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.
4 citations
,
August 2013 in “Expert Review of Dermatology” This review discusses recent advances in the diagnosis and management of female pattern hair loss but reports no new clinical results.
3 citations
,
May 2021 in “Dermatologic Clinics” This article reviews potential therapeutic targets and comorbidities associated with male androgenetic alopecia, but reports no new clinical results; further study is needed for comprehensive management.
3 citations
,
December 2018 in “Meta Gene” This study applied a prediction model based on five SNPs to Russian males with male pattern hair loss, finding a significant association between the AR genomic region and high dihydrotestosterone levels in these patients.
2 citations
,
December 2019 in “Journal of Dermatological Treatment” This study found that metabolic syndrome negatively affected the response to intradermal dutasteride injection in female pattern hair loss, with participants showing reduced terminal hair and increased vellus hair compared to those without the syndrome.
2 citations
,
December 2015 in “International Journal of Dermatology” This study found that the washing method can help differentiate chronic telogen effluvium from mild female pattern hair loss, potentially reducing the need for biopsies.
1 citations
,
May 2002 in “British Journal of Dermatology” This article provides an overview of hair density, hair diameter, and the prevalence of female pattern hair loss but reports no new clinical findings.
February 2026 in “Frontiers in Pharmacology” This review suggests a shift toward genetically informed treatments for male pattern hair loss by integrating genetic insights and pharmacogenetic markers into therapeutic decision-making.