December 2024 in “International Journal of Drug Delivery Technology” In this study, researchers developed and evaluated a topical dutasteride gel for treating male pattern baldness, finding that a formulation with 10% garlic extract showed the most promising results in promoting faster hair growth compared to other formulations tested.
June 2024 in “Archives of Dermatological Research” In this study, significant upregulation of the genes SFRP2 and PTGDS was found in bald hair follicles of female pattern hair loss patients compared to non-bald follicles, suggesting these genes may be biomarkers and play a role in hair loss for this condition.
January 2024 in “Wiadomości Lekarskie” In this study, a child's diagnosis of Silver-Russell syndrome was confirmed through phenotype data, genetic testing, and the exclusion of other developmental conditions, revealing a need for a multidisciplinary care approach.
April 2023 in “International journal of science and research” In this study, PRP treatment improved hair loss in 40 female patients with female pattern alopecia, with most progressing to better grades of hair coverage after 6 months, while only minor pain was occasionally reported as an adverse effect.
Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.
May 2002 in “British Journal of Dermatology” This brief article is a response from the authors about hair density, hair diameter, and female pattern hair loss, and it reports no new clinical findings.
30 citations
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November 2008 in “Facial Plastic Surgery” This review discusses hair transplant techniques for female pattern hair loss and reports no new clinical results; it highlights the benefits of transplants combined with various treatments for improved hair density and styling options.
29 citations
,
October 2011 in “British Journal of Dermatology” This study found that four microRNAs, which were significantly upregulated in balding hair follicle papilla cells, could play a role in the development of male pattern baldness.
26 citations
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January 2019 in “Experimental Dermatology” This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.
26 citations
,
January 2013 in “BMJ Open” This meta-analysis reports that vertex baldness is associated with an increased risk of coronary heart disease, particularly in younger men, while no significant link was found for frontal baldness.
25 citations
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June 2018 in “Clinical and Experimental Dermatology” This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.
15 citations
,
February 2018 in “Journal of Cosmetic and Laser Therapy” This study observed hair regrowth and increased density in four cases of androgenetic alopecia treated with a non-ablative erbium glass fractional laser and topical finasteride, with no significant side effects reported.
14 citations
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January 2015 in “Current problems in dermatology” This review addresses treatment approaches for female pattern hair loss, highlighting that combining different therapies may be more effective than single treatments, but no new results are reported.
5 citations
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July 2000 in “Southern Medical Journal” This review discusses available treatments for androgenetic alopecia in men, like finasteride and 5% minoxidil, and notes that hair growth results are unpredictable and often driven by industry-sponsored studies.
2 citations
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June 2019 in “International Journal of Dermatology” This study found that while a modified BASP classification for pattern hair loss could classify previously unrecognized types, it was less accurate and harder to use than the existing BASP classification.
April 2025 in “International Journal of Homoeopathic Sciences” This case report described a 29-year-old man with male pattern baldness treated with the lesser-known sarcode Adrenalin, but the abstract does not provide further details on the treatment outcome or efficacy.
March 2015 in “Polish Journal of Public Health” This study found that capillaroscopic patterns varied among patients with systemic scleroderma, psoriasis, psoriatic arthritis, and alopecia, suggesting potential microcirculation disturbances; however, no correlations were observed with serum angiogenic markers.
June 2022 in “Journal of Dermatology Research” This study found that 448-kHz Capacitive-Resistive Electrothermal Therapy led to a significant increase in hair density in women with Female Pattern Hair Loss, likely due to stimulated proliferation of dermal papilla cells.
8 citations
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January 2020 in “Biomaterials Science” In this study, small molecule-loaded silk fibroin nanofiber scaffolds with chitosan achieved sustained release of GSK-3 inhibitor SB216763, leading to enhanced wound healing and hair follicle neogenesis in skin regeneration efforts.
1 citations
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January 2014 In this study, the release rate of Finasteride from Eudragit matrix tablets was found to be significantly influenced by the drug/Eudragit ratio and polymer viscosity, with formulation F9 being the most effective.
128 citations
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August 2015 in “Cell Stem Cell” The researchers reported that dsRNA from damaged skin activates TLR3, promoting hair follicle regeneration, while TLR3-deficient animals fail to initiate this process, suggesting potential therapeutic approaches for hair neogenesis.
51 citations
,
January 2004 in “Domestic animal endocrinology” This study concluded that an endogenous circannual rhythm of prolactin secretion in mouflon influences their seasonal hair growth and moulting cycle, which varies under different photoperiodic and melatonin treatments.
46 citations
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January 2020 in “Theranostics” This study demonstrated that OSA hydrogels enhanced the stability and retention of dermal papilla-derived extracellular vesicles, which significantly improved hair regeneration in both cultured human hair and a mouse depilation model.
37 citations
,
May 2007 in “International Journal of Pharmaceutics” The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.
14 citations
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January 2015 in “Clinical Nutrition Research” This clinical trial found that the extract complex of Cistanche tubulosa and Laminaria japonica (MK-R7) significantly improved hair density and diameter in patients with patterned hair loss over 16 weeks.
10 citations
,
May 2020 in “Dermatology Research and Practice” This review discusses "follicular hypoglycania" as a potential pathology in hair growth disorders and reports that proteoglycan replacement therapy may improve hair loss treatments, though it presents no new clinical trial results.
6 citations
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December 2013 in “Journal of Cutaneous Pathology” This study found that the distribution of mast cell prostaglandin d-synthase in the scalp spatially aligns with the pattern of androgenetic alopecia, suggesting a programmed vulnerability to hair loss.
3 citations
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May 2016 in “Behavioural Brain Research” This study suggests that altering levels of the neurosteroid allopregnanolone during neonatal stages in rats may impact alcohol consumption and dopamine release in adulthood, indicating potential effects on alcohol reward properties.
January 2023 in “Frontiers in bioscience” This study suggests that Artemis, particularly phosphorylated at serine 516, may have roles in hair follicle growth by influencing differentiation, proliferation, apoptosis, and cell cycling.
December 2025 in “International Journal of Medicine and Public Health” In this study, researchers found that overt hyperthyroidism was the most prevalent thyroid disorder among patients, especially in women, and it was characterized by classic symptoms like high pulse rate and weight loss, highlighting the importance of early identification and management to prevent complications.