The Role of Photobiomodulation When Associated with Microneedling in Female Pattern Hair Loss

March 2019 in “ Medicine ”

Suzana Maria Pozzer da Silveira, Sandra Rojas Urquizas Moita, Silvia Maria Cintra da Silva, Maria Aparecida Marchesan Rodrigues, Daniela de Fátima Teixeira da Silva, Christiane Pavani

photobiomodulation microneedling female pattern hair loss FPHL PBM

Studysummary This protocol outlines a study aiming to determine if combining 660 nm red laser photobiomodulation and microneedling increases hair density in female pattern hair loss, but it reports no results yet.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This document discusses the potential benefits of combining photobiomodulation (PBM) with microneedling for the treatment of female pattern hair loss (FPHL). The authors review several studies that suggest PBM and microneedling may be effective treatments for FPHL, although more research is needed to determine the optimal treatment parameters and long-term outcomes. Overall, the authors suggest that combining PBM with microneedling may be a promising approach for treating FPHL. Additionally, there are several clinical studies outlined in the document that aim to investigate the effectiveness of combining PBM with microneedling in treating FPHL.

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Translation Into Portuguese Language (Brazil), Transcultural Adaptation and Validation of the Quality of Life Questionnaire in Female Pattern Hair Loss (WAA-QoL-BP)

research Translation Into Portuguese Language (Brazil), Transcultural Adaptation and Validation of the Quality of Life Questionnaire in Female Pattern Hair Loss (WAA-QoL-BP)

8 citations , August 2018 in “Anais Brasileiros De Dermatologia”

Researchers translated and validated the WAA-QoL questionnaire into Brazilian Portuguese, finding it to be a reliable tool for assessing quality of life in women with female pattern hair loss.

Efficacy and Safety of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial

research Efficacy and Safety of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial

31 citations , June 2018 in “Dermatologic Surgery”

In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.

A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss

research A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss

25 citations , June 2018 in “Clinical and Experimental Dermatology”

This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.

research Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review

66 citations , June 2018 in “International Journal of Women's Dermatology”

This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.

research Activation of Wnt/β-Catenin Signaling Is Involved in Hair Growth-Promoting Effect of 655-nm Red Light and LED in In Vitro Culture Model

19 citations , February 2018 in “Lasers in Medical Science”

This study found that 655-nm red light with LED enhanced hair shaft elongation and reduced catagen transition in human hair follicles in vitro by activating the Wnt/ß-catenin signaling pathway.

research Systematic Review of Low-Level Laser Therapy for Adult Androgenic Alopecia

13 citations , December 2017 in “Journal of Cosmetic and Laser Therapy”

This study evaluated the use of low-level laser therapy for treating androgenic alopecia in adults, finding it a promising and safe at-home option for stimulating hair growth compared to sham devices, though further research is needed to confirm its clinical effectiveness.

research An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata

12 citations , December 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

This review discusses platelet-rich plasma and microneedling for alopecia areata, reporting promising small-scale findings but no new results, and suggests further trials to determine efficacy and specific disease subtype suitability.

research Microneedling for the Treatment of Hair Loss

58 citations , December 2017 in “Journal of The European Academy of Dermatology and Venereology”

This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.

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33 citations , March 2017 in “Dermatologic Surgery”

In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.

research Low-Level Laser Therapy as a Treatment for Androgenetic Alopecia

47 citations , April 2016 in “Lasers in Surgery and Medicine”

This review found that low-level laser therapy appears promising in improving hair regrowth and patient satisfaction in androgenetic alopecia, though results should be interpreted cautiously.

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55 citations , January 2016 in “Annals of Dermatology”

This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.

research Female Pattern Hair Loss: An Overview

14 citations , January 2015 in “Current problems in dermatology”

This review addresses treatment approaches for female pattern hair loss, highlighting that combining different therapies may be more effective than single treatments, but no new results are reported.

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81 citations , August 2014 in “Lasers in Surgery and Medicine”

This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.

Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study

research Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study

147 citations , January 2014 in “American Journal of Clinical Dermatology”

This study found that low-level laser treatment with the HairMax Lasercomb significantly increased terminal hair density in both men and women with pattern hair loss, with no serious adverse events reported.

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53 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.

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117 citations , September 2013 in “Lasers in Surgery and Medicine”

This study found that low level laser therapy at 655 nm significantly increased hair counts in males with androgenetic alopecia.

research Quality of Life in Women with Female Pattern Hair Loss and the Impact of Topical Minoxidil Treatment

22 citations , May 2013 in “Experimental and Therapeutic Medicine”

This study found that topical minoxidil improved the quality of life in female patients with pattern hair loss.

research Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial

106 citations , April 2013 in “Dermatologic Surgery”

This study found that low-level light therapy significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, suggesting it could be an effective treatment option.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations , January 2013 in “International Journal of Trichology”

This study found that adding microneedling to minoxidil treatment significantly improved hair growth in men with androgenetic alopecia compared to minoxidil alone across all assessed measures.

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30 citations , November 2012 in “Anais Brasileiros De Dermatologia”

This review discusses chronic telogen effluvium and diffuse alopecia areata, providing clinical and diagnostic insights, but presents no new clinical findings.

research Clinical and Histological Challenge in the Differential Diagnosis of Diffuse Alopecia: Female Androgenetic Alopecia, Telogen Effluvium and Alopecia Areata – Part I

29 citations , October 2012 in “Anais Brasileiros De Dermatologia”

This review presents an objective analysis of female androgenetic alopecia, discussing clinical and dermoscopic examination approaches but reports no new clinical findings.

research Challenges in Diagnosing Female Pattern Hair Loss

5 citations , June 2012 in “Journal of Cosmetic Dermatology”

This review discusses female pattern hair loss as distinct from androgenetic alopecia and suggests that clinicians use tools like dermoscopy and histopathology for more accurate diagnosis, without reporting new findings.

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759 citations , February 2009 in “Current Biology”

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50 citations , January 2007 in “PubMed”

This review discusses female pattern hair loss, highlighting that while oral antiandrogens and topical minoxidil can arrest progression, early diagnosis and treatment are crucial, and stresses the need for ongoing therapy.

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375 citations , February 2006 in “Journal of Cell Science”

This article reviews the stages and regulation of the hair cycle, highlighting molecular regulators involved, but it does not present new research findings.

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31 citations , November 2000 in “Clinical and Experimental Dermatology”

This study developed the Women's Androgenetic Alopecia Quality of Life Questionnaire, which shows high reliability and internal consistency for assessing the impact of AGA on women's quality of life.