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Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Hair follicle regeneration possible, more research needed.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Fat cells are important for tissue repair and stem cell support in various body parts.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Men with Kennedy disease have less chance of hair loss.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Adrenal disorders can cause lasting brain and behavior issues in children.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

White hair grows thicker and faster than black hair due to higher activity of growth-related genes and proteins.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.