6 citations
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September 2021 in “AESTHETIC OROFACIAL SCIENCE” This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.
1 citations
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May 2022 in “Frontiers in medicine” This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.
1 citations
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July 2008 in “PubMed” This article reviews the protective and regenerative mechanisms of nerve fibers and Schwann cells after injury but reports no new findings.
Intermittent fasting slows hair growth by damaging hair follicle cells.
October 2022 in “Journal of Pharmaceutical Negative Results” This review examines the therapeutic effects of photobiomodulation on severe medical illnesses but reports no new clinical results; it emphasizes its potential in neurology, pulmonology, inflammation, dermatology, wound healing, and oncology.
December 2025 in “Journal of Surgery” This systematic review and meta-analysis explored the use of dermoelectroporation to enhance the delivery of exosomes derived from human placental mesenchymal stem cells, suggesting potential applications in regenerative medicine.
45 citations
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May 2019 in “Scientific Reports” This study reported that a low color temperature light (1900 K) may have positive effects on melatonin secretion, eye protection, wound healing, and hair regeneration compared to higher temperature lights.
47 citations
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December 2019 in “Biomaterials” This study demonstrated effective delivery of CRISPR/Cas9 components to dermal papilla cells in androgenic alopecia animals using ultrasound-activated nanoparticles, resulting in specific gene editing and hair growth recovery.
28 citations
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March 2017 in “African Journal of Traditional Complementary and Alternative Medicines” This study found that linseed oil, rich in flavonoids and terpenoids, significantly improved burn wound healing in terms of faster contraction, reduced inflammation, and enhanced tissue regeneration compared to other treatments, without adverse effects.
5 citations
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January 2025 in “Aesthetic Surgery Journal Open Forum” In this mouse study, researchers reported that sequential monopolar-bipolar radiofrequency irradiation significantly improved skin quality by increasing collagen density, elastin fiber expression, and fibroblast differentiation more than monopolar RF treatment alone.
2 citations
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June 2022 in “Phytomedicine” This study found that Shi-Bi-Man, a hair health supplement, significantly promoted hair growth in mice, likely through activation of the FGF signaling pathway.
1 citations
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July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that ablative fractional laser treatment significantly alters gene expression related to skin rejuvenation, enhancing wound healing and tissue regeneration processes, and suggests multiple treatments may maximize these effects.
January 2026 in “Journal of Ethnopharmacology” This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.
November 2025 in “Revista Políticas Públicas & Cidades” In this case study, the combination of microneedling and intradermal therapy was observed to effectively stimulate hair growth and improve hair density in a menopausal woman with androgenetic alopecia, resulting in enhanced self-esteem and cosmetic satisfaction.
April 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.
November 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that exosomes derived from bovine colostrum, compared to those from human stem cells, significantly increased hair follicle growth and regeneration in vitro.
November 2023 in “Food science of animal resources” This study found that in mice, oral administration of Lactilactobacillus curvatus LB-P9 accelerated hair regrowth and increased hair thickness, hair follicle numbers, and dermal thickness, likely by boosting hair growth factor production and dermal papilla proliferation.
May 2026 in “Journal of Medicinal Food” This study found that orally administered hydrolyzed keratin peptide promoted hair growth and enhanced cellular proliferation and antioxidant capacity in mice and human cell models, suggesting its potential as a functional food ingredient for hair health.
December 2025 in “PubMed” This study suggests that low molecular weight fish collagen peptide may promote hair follicle growth and regeneration, improving overall hair quality in mouse models.
This study found that exosomes derived from human umbilical cord mesenchymal stem cells effectively promoted growth in human hair dermal papilla cells, implicating the PI3K and Akt pathways as potential targets for treating hair loss.
February 2025 in “Clinical Medical Reviews and Reports” In this study, autologous platelet-rich plasma was associated with improved burn wound healing in a 45-year-old male, showing potential as an adjunctive therapy, but broader trials are needed to confirm its effectiveness.
This study observed that methylene blue, a mitochondrial-targeted antioxidant, promotes hair follicle stem cell proliferation and viability through reduced oxidative stress and enhanced β-catenin signaling, and it may also protect against hair loss related to glucagon-like peptide-1 receptor agonists by reducing metabolic stress.
November 2025 in “EXPERIMENTAL ANIMALS” In this murine study, researchers found that topical treatment with Philippine stingless bee propolis increased folliculogenesis, epidermal thickness, and melanogenesis, but not hair length, potentially supporting hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia models.
May 2025 in “Scientific Reports” This study found that oxyresveratrol enhanced cell proliferation, reduced oxidative stress and inflammation in vitro, and promoted hair growth in an androgenetic alopecia mouse model, suggesting its potential as a treatment for hair loss.
February 2026 in “Journal of Korea Society of Ingrielogy” This review discusses the potential immuno-regenerative effects of polydioxanone threads in hair loss treatment, focusing on tissue responses and immune modulation, but does not report clinical results.
32 citations
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June 2021 in “Frontiers in Pharmacology” This study reports that Cur@CMCTS-Tk hydrogel effectively accelerated wound healing and tissue regeneration in rats by scavenging excess reactive oxygen species and protecting human fibroblasts from oxidative damage.
21 citations
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October 2025 in “Advanced Materials” This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.
19 citations
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April 2015 in “Stem Cells” This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.
18 citations
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October 2013 in “Stem Cell Research & Therapy” This study found that combining polybrene and a ROCK inhibitor can effectively expand human keratinocyte stem/progenitor cells carrying a transgene, aiding their use in regenerative medicine.
17 citations
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December 2019 in “Stem Cell Research & Therapy” This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.