Dermoelectroporation-Enhanced Delivery of Human Placental Mesenchymal Stem Cell-Derived Exosomes for Regenerative Applications: A Systematic Review and Meta-Analysis
December 2025
in “
Journal of Surgery
”
New to Exosomes? There is a guide in the encyclopedia. Read the guide → Studysummary This systematic review and meta-analysis explored the use of dermoelectroporation to enhance the delivery of exosomes derived from human placental mesenchymal stem cells, suggesting potential applications in regenerative medicine.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This systematic review and meta-analysis evaluates the effectiveness of dermoelectroporation-enhanced delivery of human placental mesenchymal stem cell-derived exosomes for regenerative applications. The study synthesizes data from multiple trials to assess the potential benefits of this delivery method in promoting tissue regeneration. The findings suggest that this technique significantly enhances the delivery and efficacy of exosomes, leading to improved regenerative outcomes. The analysis includes a comprehensive review of existing literature, highlighting the promising role of this advanced delivery system in regenerative medicine. However, further research with larger sample sizes is recommended to validate these findings and optimize treatment protocols.