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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
1 citations,
November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
7 citations,
September 2020 in “Frontiers in Cell and Developmental Biology” IL-36α helps grow new hair follicles and speeds up wound healing.
21 citations,
June 2018 in “Current Opinion in Genetics & Development” Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
February 2024 in “Pharmaceutics” Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
43 citations,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
21 citations,
October 2009 in “Biochemical Engineering Journal” Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
39 citations,
April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
20 citations,
May 2015 in “Regenerative Medicine” The document warns against US clinics selling untested stem cell treatments without FDA approval.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
1 citations,
February 2020 in “Regenerative Medicine” Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.
78 citations,
June 2013 in “Science” Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.
43 citations,
January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
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April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
November 2023 in “Periodontology 2000” Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.
271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
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March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
January 2024 in “Journal of developmental biology” Abdominal skin heals faster than dorsal skin because it has more stem cells.
176 citations,
June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
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December 2021 in “Regenerative Biomaterials” The hydrogel speeds up skin wound healing and helps regenerate tissue.
188 citations,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
182 citations,
June 2017 in “Biomaterials” Special fiber materials boost the healing properties of certain stem cells.
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April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
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May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
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November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.