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New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Smoking may worsen hair loss, but more research is needed.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Malondialdehyde-modified DNA may trigger an immune response in alopecia areata patients.

Oral zinc sulphate reduces dark hair color in mice.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.

taVNS reduces vitiligo symptoms in mice.

Grape seed extract may safely and effectively help prevent lung cancer.

Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Applying calreticulin can speed up wound healing in diabetics.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Exosomes show promise for future tissue regeneration.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

Manipulating cell cleanup processes could help treat hair loss.