Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice

This study investigates the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on monobenzone-induced vitiligo in mice. The results show that taVNS significantly alleviates vitiligo symptoms by reducing depigmented areas, enhancing melanin production, and improving hair follicle health. It also decreases oxidative stress, increases antioxidant enzyme activities, and reduces inflammatory responses by lowering proinflammatory cytokines and CD8+ T cell infiltration. These findings suggest that taVNS could be a promising noninvasive therapy for vitiligo, warranting further research into its mechanisms and clinical applications.