research Role of Stem/Progenitor Cells in Reparative Disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
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270-300 / 1000+ results research Integument Pattern Formation Involves Genetic and Epigenetic Controls: Feather Arrays Simulated by Digital Hormone Models
Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
research Disruption of the Temporally Regulated Cloaca Endodermal β-Catenin Signaling Causes Anorectal Malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research Failure to Induce Alopecia Areata in C3H/HeJ Mice with Exogenous Interferon Gamma
Interferon gamma alone can't cause alopecia areata in C3H/HeJ mice.
research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model
Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating
Krt15+ cells in the mouse intestine resist radiation and can start tumors.
research Current Protocols: Alopecia Areata Mouse Models for Drug Efficacy and Mechanism Studies
The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.
research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
research Skin CD4+ Memory T Cells Exhibit Combined Cluster-Mediated Retention and Equilibration with the Circulation
Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Mesenchyme Governs Hair Follicle Induction
The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
research Decision Letter: Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Omega-6 Highly Unsaturated Fatty Acids in Leydig Cells Facilitate Male Sex Hormone Production
Omega-6 fats in certain cells boost male hormone production.
research Knockout of Integrin Beta1 in Induced Pluripotent Stem Cells Accelerates Skin-Wound Healing by Promoting Cell Migration in Extracellular Matrix
Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
research Endogenous Retinoids in the Pathogenesis of Alopecia Areata
Vitamin A affects hair loss and immune response in alopecia areata.
research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
research Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Skin stem cells in hair follicles are important for touch sensation.
research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
research Intradermal Adipocytes Mediate Fibroblast Recruitment During Skin Wound Healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Hair Cycle Control by Leptin as a New Anagen Inducer
Leptin, a hormone, is important for starting hair growth.
research CXCL12 Inhibits Hair Growth Through CXCR4
CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.
research Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition
Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
research Down-Regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in Xenopus Melanophores
Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Hydrogel Crosslinking Modulates Macrophages, Fibroblasts, And Their Communication During Wound Healing
Softer hydrogels help wounds heal better with less scarring.