research Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration
The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
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330-360 / 1000+ results research SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice
SIRT7 protein is crucial for starting hair growth in mice.
research Efficacy of Dupilumab in Treating Atopic Dermatitis With Recurrent Eczema Herpeticum in a Patient With DOCK8-Deficiency Hyper-IgE Syndrome: A Case Report
Dupilumab helped improve skin and prevent new lesions in a child with a rare immune disorder and severe eczema.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
Hair color is determined by melanin produced and transferred in hair follicles.
research Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts
Minoxidil boosts elastin production, potentially helping skin diseases.
research Procyanidin Oligomers Counteract TGF-β1- and TGF-β2-Induced Apoptosis in Hair Epithelial Cells: An Insight into Their Mechanisms
Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.
research Transforming Growth Factor-Alpha Immunoreactivity During Induced Hair Follicle Growth Cycles in Sheep and Ferrets
TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.
research Induction of Hyperandrogenism and Insulin Resistance Differentially Modulates Ferroptosis in Uterine and Placental Tissues of Pregnant Rats
HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Pharmacologic Treatment of Polycystic Ovary Syndrome
The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Mechanical Forces Across Compartments Coordinate Cell Shape and Fate Transitions to Generate Tissue Architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research An Industry Update: What's New in the Field of Therapeutic Delivery This Month?
New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.
research Platelet-Rich Plasma: The Ultimate Secret for Youthful Skin Elixir and Hair Growth Triggering
Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
research Oral Administration of Lactilactobacillus Curvatus LB-P9 Promotes Hair Regeneration in Mice
Lactilactobacillus curvatus LB-P9 taken orally helps hair regrow faster and thicker in mice.
research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors
Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.
research A Review of the Evidence for and Against a Role for Mast Cells in Cutaneous Scarring and Fibrosis
Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Activation of Astrocytes In Vitro by Macrophages Polarized with Keratin Biomaterial Treatment
Keratin treatment reduces astrocyte reactivity and inflammation.
research Toward Understanding Scarless Skin Wound Healing and Pathological Scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Expression of the Orphan Protein Plet-1 During Trichilemmal Differentiation of Anagen Hair Follicles
Plet-1 protein helps hair follicle cells move and stick to tissues.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Efficacy of Derinat as a Treatment for Murine and Androgenetic Alopecia Patients
Derinat may improve hair growth and quality of life in hair loss patients by reducing oxidative stress.
research Single-Cell Transcriptomics Reveals a Senescence-Associated IL-6/CCR6 Axis Driving Radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Hair Growth in a Patient with Alopecia Areata on Tocilizumab
A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.
research Combined Therapy with Adipose Tissue-Derived Mesenchymal Stromal Cells and Meglumine Antimoniate Controls Lesion Development and Parasite Load in Murine Cutaneous Leishmaniasis Caused by Leishmania Amazonensis
Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
research Dissecting the Impact of Chemotherapy on the Human Hair Follicle
Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
research Gene Therapy: Recent Advances and Applications in Dermatology
Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.