Hair Growth in a Patient with Alopecia Areata on Tocilizumab

    January 2021 in “ Skin appendage disorders ”
    Chloe J. Walker, Kelly Flanagan, James T. Pathoulas … Maryanne M. Senna
    Studysummary This case report describes a 21-year-old woman with progressive alopecia areata who experienced hair regrowth while treated with tocilizumab for posterior uveitis, suggesting the potential for this drug to affect hair loss and regrowth by disrupting interleukin-6 signaling.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    2. An Integrated Model of Alopecia Areata Biomarkers Highlights Both TH1 and TH2 Upregulation Journal of Allergy and Clinical Immunology · 2018
    3. Halo Nevi, Vitiligo, and Diffuse Alopecia Areata Associated with Tocilizumab Therapy Oxford Medical Case Reports · 2016
    4. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    5. Hair-Cycle Changes in Two Patients Taking Tocilizumab Joint Bone Spine · 2013
    6. Telogen Effluvium: A Review of Acute and Chronic Forms Indian Journal of Dermatology, Venereology and Leprology · 2013
    7. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011

    Related research 5

    1. Trachyonychia in a Child with Concomitant Alopecia Areata and Lichen Planus International journal of research in dermatology · 2021
    2. Hair Growth in a Patient with Alopecia Areata on Tocilizumab Skin appendage disorders · 2021
    3. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    4. Interventions for Alopecia Areata Journal of Evidence-Based Medicine · 2009
    5. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983