113 citations,
June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
26 citations,
July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
June 2020 in “Journal of Investigative Dermatology” The technique effectively shows how human skin and hair cells form into ball-like structures.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
13 citations,
November 2010 in “Experimental Dermatology” Vitamin C derivative reduces hair loss-related protein in cells.
7 citations,
December 2020 in “ACS biomaterials science & engineering” Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.
87 citations,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
59 citations,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
48 citations,
July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
21 citations,
January 2018 in “The Korean Journal of Physiology and Pharmacology” Modified stem cells from umbilical cord blood can make hair grow faster.
19 citations,
May 2020 in “Cells” Substance from human umbilical cord blood cells promotes hair growth.
16 citations,
January 2018 in “Biochemical and Biophysical Research Communications” Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.
13 citations,
January 2015 in “Toxicology Letters” Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
10 citations,
May 2019 in “BMC Complementary and Alternative Medicine” The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
10 citations,
November 2018 in “Genetics in medicine” Lack of cystatin M/E causes thin hair and dry skin.
10 citations,
December 2011 in “Cell Transplantation” Researchers successfully grew human hair follicle cells that could potentially lead to new hair loss treatments.
6 citations,
January 2018 in “Journal of Cellular Physiology” Human scalp fat stem cells showed improved cartilage-like development on a special scaffold with freeze-thaw treatment.
6 citations,
January 2016 in “Annals of Dermatology” Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.
2 citations,
January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
August 2024 in “Biomolecules & Therapeutics” A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
October 2023 in “Scientific reports” Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
136 citations,
March 1996 in “Journal of the American Chemical Society” Finasteride effectively blocks enzyme causing male pattern baldness.
49 citations,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
39 citations,
March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
22 citations,
October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
47 citations,
May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
44 citations,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
17 citations,
May 2010 in “Journal of Dermatological Science” Erythropoietin helps hair grow and could be a potential treatment for hair loss.