January 2016 in “Minerva Access (University of Melbourne)” This dissertation found that hair follicle transplantation promoted wound healing in mice by enhancing wound re-epithelialization and increasing nerve density in the granulation tissue.
January 2014 in “Durham e-Theses (Durham University)” In this study, the activation of Notch1 signaling in keratinocytes was found to play a key role in recruiting immune cells and facilitating skin repair after injury.
June 2008 in “Wound Repair and Regeneration” In this study, Msx-2 knockout mice showed enhanced re-epithelialization and faster wound closure compared to wild-type controls, suggesting Msx-2 may influence skin morphogenesis during wound repair.
August 2007 in “Journal of Investigative Dermatology” This review covers presentations from the 68th Annual Meeting of the Society of Investigative Dermatology and highlights research advances in dermatology, but reports no new clinical results.
June 2006 in “Experimental dermatology” This study found that, while hair follicle bulge stem cells are important for hair follicle survival and epidermal regeneration after wounding, the epidermis maintains itself independently of these cells under normal conditions.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.
131 citations
,
March 2004 in “The American journal of pathology” This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.
95 citations
,
June 2002 in “The Journal of Dermatology” In this study, using topical crude onion juice significantly improved hair regrowth in patients with patchy alopecia areata compared to tap water.
81 citations
,
September 2005 in “The American journal of pathology” This study found that activin affects both stromal cells and keratinocytes in skin morphogenesis and repair, with dose-dependent effects on keratinocytes demonstrated through transgenic mouse models.
57 citations
,
January 2024 in “ACS Nano” This study found that black phosphorus nanosheets positively influence skin repair by enhancing angiogenesis, anti-inflammatory response, collagen deposition, and re-epithelialization in a rat model of skin wounds, potentially through activating the JAK-STAT-OAS signaling pathway.
52 citations
,
September 2018 in “International Journal of Molecular Sciences” This review highlights the potential of ginseng and its metabolites in preventing hair loss, detailing their hair growth-promoting effects observed in numerous preclinical studies, and emphasizing the underlying mechanisms involved.
43 citations
,
July 2014 in “Experimental Dermatology” This review explores the relationship between hair follicles and wound healing, emphasizing the importance of translating scientific findings into practical therapies for chronic wounds, but it reports no new experimental results.
32 citations
,
February 2024 in “Growth Hormone & IGF Research” In this study, DHT was found to inhibit hair growth in mice by decreasing IGF-I production in dermal papillae through reduced sensory neuron stimulation.
26 citations
,
June 2020 in “Polymers” This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.
22 citations
,
January 1992 in “PubMed” This preliminary study suggests that baseline central serotonin turnover, indicated by CSF 5-HIAA levels, may influence treatment response to serotonin re-uptake inhibitors in women with trichotillomania.
21 citations
,
January 2015 in “Journal of Dermatological Science” This study investigates the potential hair growth effects of Panax ginseng and its ginsenosides on human hair follicles, suggesting mechanisms similar to those of minoxidil.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.
18 citations
,
December 2015 in “PubMed” This study found that intralesional triamcinolone was more effective than topical betamethasone for hair regrowth in patients with localized alopecia areata.
13 citations
,
July 2020 in “World journal of stem cells” This review discusses vitamin D and calcium signaling roles in epidermal stem cell processes essential for wound healing but reports no new experimental results, emphasizing their potential interdependent regulatory mechanisms.
8 citations
,
December 2015 in “PubMed” In this study, petroleum ether extracts of Phyllanthus niruri promoted hair regrowth in testosterone-induced alopecia in rats by inhibiting the 5α-reductase enzyme.
6 citations
,
October 2024 in “Frontiers in Bioengineering and Biotechnology” This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.
5 citations
,
February 2022 in “International Journal of Molecular Sciences” This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.
3 citations
,
March 2019 in “PubMed” In this report, Biofibre® medical hair prosthetic fibers were shown to meet safety and biocompatibility standards, offering immediate aesthetic results for hair loss treatment with minor surgical intervention and reversible implantation, but requiring good after-care and yearly maintenance for optimal cosmetic outcomes.
3 citations
,
January 2016 in “Biotechnology and Bioprocess Engineering” This animal study found that Laminaria japonica mixed with insulin-like growth factor-1 significantly promoted hair growth in mice, suggesting its potential use for treating alopecia pending further clinical trials.
March 2026 in “International Journal of Molecular Sciences” This study found that Grateloupia angusta extract improved wound healing by promoting matrix production and pro-angiogenic activity in cell cultures and enhanced early wound repair in a mouse skin incision model.
February 2024 in “Research Square (Research Square)” In this study, researchers found that exosomes derived from dermal papilla cells can enhance hair follicle regeneration during wound healing in nude mice by promoting fibroblast activation and stimulating the Wnt/β-catenin signaling pathway, suggesting their potential as a therapeutic strategy for regenerative skin healing.
November 2023 in “Pakistan Journal of Health Sciences” This study found that clobetasol propionate 0.05% was significantly more effective in stimulating hair re-growth in alopecia areata patients compared to topical tacrolimus 0.1%, with an excellent response observed in 74.3% of the clobetasol group versus 40% in the tacrolimus group.
May 2023 in “Hair transplant forum international” This case study describes a successful reconstructive treatment for a patient with a frontoparietal giant congenital melanocytic nevus, achieved through collaboration between plastic and hair restoration surgeons.
July 2022 in “المجلة العراقية للصيدلة” This study found that among women with hirsutism, the most common type of non-scarring hair loss observed was androgenetic alopecia with telogen effluvium.
January 2022 in “Social Science Research Network” This study found that activating both PKM2 and Wnt/β-catenin signaling enhanced hair re-growth and HFSCs proliferation in mice, suggesting a potential treatment strategy for alopecia.