46 citations,
February 1983 in “The Journal of Dermatology” The study investigated hair regrowth in C3H mice of varying ages by analyzing enzyme activities in different skin areas after shaving. It was found that hair regrowth was irregular and delayed as mice aged, with older mice showing more significant delays. In 59-day-old mice, 30-50% of the shaved area was covered with new hair nine days post-shaving. Biochemical analysis revealed that enzyme activities of ornithine decarboxylase (ODC), transglutaminase (TGase), and alkaline phosphatase (Al-P) were significantly higher in hair re-growing areas compared to non-growing areas. These enzyme activities were also elevated in follicle-rich fractions from re-growing areas compared to non-shaved areas, suggesting a link between these enzymes and hair growth.
39 citations,
January 2016 in “Journal of Cutaneous and Aesthetic Surgery” Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.
39 citations,
January 2010 in “Trends in Parasitology” Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.
33 citations,
August 1973 in “American Heart Journal” Propranolol can cause reversible hair loss.
32 citations,
January 2015 in “Annals of diagnostic pathology” The document concludes that recognizing oral lesions is important for diagnosing syphilis.
31 citations,
June 2017 in “Regeneration” BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.
29 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
26 citations,
January 2018 in “Annals of dermatology/Annals of Dermatology” Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
26 citations,
November 2011 in “Arquivos Brasileiros De Endocrinologia E Metabologia” Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.
23 citations,
November 2018 in “International Journal of Molecular Sciences” Deoxyshikonin helps wounds heal faster in diabetic mice.
20 citations,
January 2013 in “Annals of Dermatology” Topical minoxidil successfully treated temporal triangular alopecia.
18 citations,
November 2016 in “PeerJ” Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
16 citations,
January 1998 in “Dermatology” Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.
15 citations,
June 2018 in “Life Sciences” Diabetex improves diabetic wound healing better than metformin.
13 citations,
July 2010 in “Drug safety” Lamotrigine may cause hair loss, affecting treatment compliance and health.
11 citations,
July 2021 in “Sustainability” Concrete made from animal bones and human hair is stronger and more environmentally friendly than traditional concrete.
11 citations,
April 2017 in “The European Journal of Contraception & Reproductive Health Care” Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
10 citations,
December 2002 in “International Journal of Dermatology” Cyproterone acetate can cause rare shortness of breath in women.
9 citations,
October 2020 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil is an effective and well-tolerated treatment for hair growth in alopecia patients.
9 citations,
July 2014 in “Experimental Dermatology” PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.
8 citations,
May 2019 in “Journal of dermatological treatment” Vismodegib is effective for basal cell carcinoma but has severe side effects.
8 citations,
October 2016 in “Journal of Investigative Dermatology” MR antagonists may improve skin health and wound healing, especially in aging.
8 citations,
March 1994 in “The American Journal of Cosmetic Surgery” The Total Excision Techniques improve hair transplant results by increasing grafts by at least 50% and reducing scarring.
7 citations,
January 2019 in “Journal of Analytical Toxicology” Tramadol and THC-COOH can be detected in hair for several months after stopping use.
7 citations,
December 2017 in “Anais da Academia Brasileira de Ciências” 6-Gingerol from ginger may slow down hair growth by affecting certain enzymes and growth factors.
6 citations,
December 2017 in “PubMed” Minoxidil helps hair growth by promoting stem cell differentiation through increased ATP synthase activity.
6 citations,
August 2005 in “Facial Plastic Surgery Clinics of North America” Specific techniques can make facelift results look more natural.
5 citations,
January 2023 in “Fertility and sterility” Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.
5 citations,
January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
4 citations,
May 2017 in “Data in Brief” Five molecular elements identified as potential future targets for hair loss therapy.