70 citations
,
February 2017 in “Dermatologic Surgery” This study reports that plasma rich in growth factors appeared to improve hair follicle regeneration and patient satisfaction in individuals with androgenetic alopecia, though further trials are needed.
67 citations
,
November 2002 in “Journal of The American Academy of Dermatology” This review discusses diagnostic approaches for women with diffuse, nonscarring hair loss and reports no new clinical results.
64 citations
,
June 2014 in “Journal of The American Academy of Dermatology” This study found that a peripilar white gray halo around hair emergence is a highly specific and sensitive dermatoscopic feature for diagnosing central centrifugal cicatricial alopecia in African American patients with mild central thinning.
63 citations
,
August 2008 in “Journal of Cosmetic Dermatology” The researchers reported that the petroleum ether extract of Cuscuta reflexa may promote hair growth in testosterone-induced alopecia in mice by inhibiting the enzyme 5α-reductase.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.
50 citations
,
August 2017 in “Diabetologia” This review discusses genetic factors that may influence the effectiveness of metformin in treating polycystic ovary syndrome and emphasizes the need for further research to establish clear benefits.
49 citations
,
June 2003 in “European journal of cardiovascular prevention & rehabilitation” In this study, female androgenic alopecia (grade II or III on Ludwig's scale) was found to be common among Finnish women aged 63, and several markers of insulin resistance, along with paternal history of alopecia, were associated with an increased risk.
46 citations
,
November 2014 in “Journal of Cutaneous Pathology” This study describes the diverse histopathological patterns and clinical features observed in patients with folliculotropic mycosis fungoides, emphasizing the importance of accurate recognition to avoid diagnostic errors.
45 citations
,
January 2013 in “Journal of Human Reproductive Sciences” In this study, women with PCOS had a higher prevalence of hepatic steatosis compared to controls, with associated metabolic issues like insulin resistance and metabolic syndrome.
44 citations
,
August 2012 in “Journal of Food Science” This study optimized conditions for extracting saponins from Eclipta prostrata, achieving maximum yield with specific ethanol concentration, time, temperature, and liquid/solid ratio.
41 citations
,
May 2001 in “PubMed” This study proposes a new clinical scoring method for hair density based on hair diameter diversity, which correlates with existing measures and reflects follicle miniaturization in androgenetic alopecia.
36 citations
,
November 1995 in “Clinical endocrinology” This study found that a low dose of flutamide, both alone and combined with an oral contraceptive, effectively reduced hirsutism in women, with the combination showing more lasting effects post-treatment.
33 citations
,
November 2007 in “JAT. Journal of applied toxicology/Journal of applied toxicology” In this study, human scalp hair grafted onto nude mice accurately reflected methyl mercury exposure, demonstrating its potential as a research model for monitoring mercury incorporation into human hair.
32 citations
,
October 2009 in “Dermatology” This article describes acute and chronic telogen effluvium, highlighting the importance of differentiating them from androgenetic alopecia for accurate diagnosis and treatment strategies but includes no new clinical research findings.
31 citations
,
December 2023 in “Middle East Fertility Society Journal” This review discusses the relationship between polycystic ovary syndrome and inflammation, highlighting various inflammatory markers, but reports no new clinical results.
31 citations
,
August 2001 in “PubMed” This study found that the TrichoScan method detected significant increases in hair counts and cumulative hair thickness in men after finasteride treatment, suggesting its potential for monitoring hair treatment responses.
30 citations
,
April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry” This study found that using hair steroid profiling, dutasteride treatment led to reduced dihydrotestosterone levels and DHT/testosterone ratio in patients with male-pattern baldness.
28 citations
,
April 2014 in “Hormones” This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.
28 citations
,
December 2002 in “Der Hautarzt” TrichoScan accurately measures hair growth and loss, showing increased hair counts and thickness with treatment.
27 citations
,
January 2010 in “Animal” In these studies, researchers found that Peruvian camelids reach mature skin follicle development early, with specific cuticular characteristics useful for distinguishing fleece types, while Bolivian llamas have a mature follicle apparatus present at birth.
26 citations
,
March 2015 in “Phytotherapy Research” This study found that forsythiaside-A, a natural compound from Forsythia suspensa, was more effective than finasteride at preventing apoptosis of hair cells and delaying the catagen phase entry in an androgenic alopecia mouse model.
25 citations
,
October 1993 in “American Journal of Physical Anthropology” This study observed that in Namibian/Southern African men, hormone levels, particularly estradiol, influence the growth of body hair, with different effects noted in various ethnic groups.
24 citations
,
June 2021 in “Agronomy” This study found that biostimulant application in lettuce cultivation led to significant yield and phytochemical enhancements, with effects varying between green and red cultivars depending on the treatment method used.
24 citations
,
September 2012 in “Dermatologic Surgery” The conclusion is that normal scalp hair counts for Taiwanese people were established, showing age-related differences but not sex or scalp location differences.
22 citations
,
August 2013 in “International journal of gynaecology and obstetrics” This study found that GAGS scores for acne were higher in younger women with PCOS and a lower BMI, but showed no association with levels of androgen hormones.
22 citations
,
January 2012 in “Obstetrics and Gynecology International” In this study of Bulgarian women, the waist-to-stature ratio was a better marker for an unfavorable metabolic profile than the waist-to-hip ratio among those with PCOS and obesity.
21 citations
,
January 2020 in “Pharmaceutical Biology” In this study, Salvia plebeia extract promoted hair growth by enhancing proliferation and anti-apoptotic effects in human dermal papilla cells and increased hair growth in treated mice.
21 citations
,
November 2010 in “Talanta” This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.
20 citations
,
February 2004 in “Veterinary dermatology” This study found that the season of the year does not significantly affect the hair regrowth rate or the telogen: anagen ratio in indoor-housed Labrador retrievers.
19 citations
,
May 2017 in “Dermatologic Surgery” Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.