Prevalence of Hepatic Steatosis in Women with Polycystic Ovary Syndrome

    January 2013 in “ Journal of Human Reproductive Sciences ”
    Ritu Karoli, Jalees Fatima, Ashok K. Chandra, Uma Gupta, Faraz-Ul Islam, Gagandeep Singh
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    TLDR Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
    The study investigated the prevalence of nonalcoholic fatty liver disease (NAFLD) in 54 women with polycystic ovary syndrome (PCOS) compared to 55 healthy controls, finding a significantly higher occurrence of hepatic steatosis in the PCOS group (67% vs. 25%, P = 0.001). Additionally, women with PCOS had more cases of metabolic syndrome (35% vs. 7%, P < 0.01) and elevated transaminases (31% vs. 7%, P = 0.03). Factors linked to hepatic steatosis included age, body mass index (BMI), waist-hip ratio, insulin resistance, HDL levels, and a PCOS diagnosis. The study concluded that NAFLD is common in women with PCOS, particularly those with metabolic issues, and that liver disease evaluation should be considered earlier in these patients, especially if they show signs of metabolic syndrome.
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