February 2010 in “Journal of The American Academy of Dermatology” This study found that nonobese women with idiopathic hirsutism exhibited lower nitrite/nitrate concentrations and higher fibrinogen levels compared to control subjects, but these were similar to levels in women with polycystic ovary syndrome.
June 2024 in “Trends in Urology & Men s Health” This study explores the controversial condition known as post‐finasteride syndrome, observed in some men who experience lasting sexual, neurological, and psychological side effects after stopping finasteride, emphasizing its rarity and the lack of proven treatments.
January 2021 in “Menoufia Medical Journal (Print)” This study reported that androgenetic alopecia affects the psychosocial aspects and quality of life differently depending on marital status and occupational category, with married patients and professional workers experiencing higher emotional impact.
6 citations
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January 2020 in “BMC Neuroscience” In this study, male-derived brain tissue exhibited higher cell death following ischemia compared to female-derived tissue, and certain steroid hormones showed different neuroprotective effects depending on the sex of the tissue.
July 2020 in “European urology open science” Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.
This review explores historical and cultural perspectives on human hair's significance and reports no clinical findings on its function or health impact.
24 citations
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May 2015 in “Schizophrenia Research” This study found that inhibiting the enzyme 5α-reductase with finasteride counteracted stress-induced prepulse inhibition deficits in socially isolated rats by altering neuroactive steroid concentrations in the brain.
5 citations
,
July 2016 in “Canadian Urological Association journal” This study suggests that age, androgenetic alopecia, metabolic syndrome, and free testosterone levels may significantly affect sexual function in premenopausal women.
3 citations
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September 2025 in “Neural Regeneration Research” This review discusses the roles of prostaglandins in the nervous system and their therapeutic potential for neurological diseases, noting their complex interactions with immune cells and signaling pathways.
10 citations
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November 2000 in “Aesthetic Surgery Journal” Secondary aesthetic surgeries for gender reassignment are generally satisfying and advance overall aesthetic surgery techniques, but psychological support is important.
60 citations
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June 2007 in “Pharmacology Biochemistry and Behavior” In this study, withdrawal from progesterone and treatment with finasteride were associated with increased signs of depression-like behavior in female mice, suggesting decreased allopregnanolone levels may play a role.
27 citations
,
May 2008 in “Neuroscience” This study found that altering neonatal neurosteroid levels affected anxiety and aversive learning in adult rats, possibly through changes in hippocampal GABAergic functions.
4 citations
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March 2019 in “JAT. Journal of applied toxicology/Journal of applied toxicology” In this study, PFOS exposure altered steroid hormone levels and enzyme activities related to steroidogenesis in juvenile Silurana tropicalis, with effects differing between male and female frogs.
30 citations
,
July 2023 in “Journal of Cutaneous Medicine and Surgery” This article emphasizes the need for dermatology to treat gender identity, gender, and sex as distinct factors, aiming to improve patient-specific risk assessment and treatment alignment, and highlights a research gap in distinguishing sex and gender as separate risk factors in the field.
January 2011 in “InTech eBooks” This article reviews the development, classification, and embryology of hypospadias and reports no new findings; the authors highlight its unknown cause and discuss associated anatomical anomalies.
April 2018 in “The Journal of Urology” In this study, men with pre-diabetes seeking treatment for erectile dysfunction had worse hormonal and metabolic profiles and a higher risk of severe erectile dysfunction compared to those without pre-diabetes.
1 citations
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May 2018 in “Clinical chemistry” This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.
March 2024 in “Journal of the American Academy of Dermatology” Taking medication for hair loss might cause sexual problems.
22 citations
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January 2008 in “Physiological Research” This review discusses the role of steroid sulfatase in steroid hormone metabolism and highlights the need for more research on its expression and regulation, especially regarding hormone-dependent tumors.
22 citations
,
November 2020 in “International Journal of Environmental Research and Public Health” This study found that hidradenitis suppurativa significantly impacts patients' sexuality, with many experiencing fear of rejection, perceived unattractiveness, and negative effects on relationships and sexual activity.
This study provides genomic and epigenomic insights into the white wax scale insect, highlighting high methylation levels and differential hormone profiles linked to its sexual dimorphism and developmental differences.
1 citations
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January 2017 in “Endokrynologia Pediatryczna” This review concludes that polycystic ovary syndrome can significantly impact aspects of health-related quality of life in adolescent girls, especially body image and interpersonal functioning.
4 citations
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March 2022 in “Journal of The American Academy of Dermatology” This study found an association between finasteride use and increased reporting of suicidality and depression in young patients with androgenetic alopecia, potentially mediated by sexual dysfunction.
44 citations
,
January 1999 in “Advances in pharmacology” This chapter reviews recent findings on androgen receptor function, structure, and interactions, highlighting post-translational modifications and mutations related to prostate cancer, but reports no new experimental results.
97 citations
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March 2009 in “Dermato-endocrinology” This review explores the role of hormones in pilosebaceous units and associated skin disorders, focusing on androgen action, without presenting new clinical findings.
2 citations
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March 2008 in “Hair transplant forum international” This study found that male patients who underwent hair transplant surgery reported significant improvements in self-esteem, emotional well-being, and aspects of their sex life and career compared to before the surgery.
1 citations
,
March 2025 in “Medical Molecular Morphology” This review discusses how androgens, commonly known for male reproductive roles, also influence the physiology and pathology of the human endometrium, though their exact roles in this tissue remain controversial and not fully understood.
1 citations
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May 2019 in “The Journal of Sexual Medicine” This case report describes two women experiencing hormonally associated vestibulodynia and female arousal disorder, potentially linked to the use of spironolactone for androgen-mediated cutaneous disorders.
April 2022 in “The Journal of Sexual Medicine” This study reports that simultaneous cystoscopy, electroejaculation, transurethral resection of ejaculatory ducts, and seminal vesiculography were safe and effective in diagnosing and treating concurrent hematospermia and anorgasmia.