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Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.

This review examines existing research on transdermal testosterone for treating hypoactive sexual desire disorder, suggesting it improves female sexual function with minimal side effects but highlights the need for more long-term safety data.

This chapter discusses the role of orthognathic surgeons in facial feminization surgery, focusing on procedures such as forehead reduction and orbital rim contouring, but reports no new clinical results.

This case study highlights the complexity of managing PCOS and its symptoms in transmen, suggesting hormonal fluctuations may lead to symptomatic relief with low dose estradiol.

This study found that exposure to certain pesticides may be associated with delayed sexual maturation in adolescent males.

In this study, progesterone showed anticonvulsant effects in mice via a mechanism that is at least partially independent of its metabolism to THP, without significant psychotoxicity.

This study found that scalp micropigmentation significantly improved psychological well-being among adults by enhancing appearance satisfaction and perceived physical attractiveness, but not through a direct relationship with psychological well-being itself.

This research emphasizes the importance of integrating pre-treatment psychological assessments for individuals considering finasteride, highlighting that these assessments could help identify those prone to nocebo responses, potentially reducing adverse symptom development more related to cognitive vulnerabilities than to the drug itself.

This paper discusses the role of androgen hormones in regulating sebum production and hair growth via androgen receptors in the pilosebaceous unit, but reports no new findings.

In this study, a computational analysis of promoter regions in human fertility-related genes identified several new candidate regulatory motifs, but these require further experimental validation due to the limitations of being an in silico examination.

This study found that dutasteride use was associated with a stable decrease in sexual function over four years, with no additional risk based on age or prostate size.

This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.

This study found that local synthesis of 17β-estradiol and 5α-dihydrotestosterone, combined with specific stimulation patterns, is crucial in determining the direction and strength of long-term synaptic effects in the hippocampal CA1 region of male rat slices.

Androgens and other hormones affect hair growth and skin conditions like acne.

This case report describes a girl with familial adenomatous polyposis who exhibited heterosexual precocious puberty due to an adrenal tumor secreting cortisol and androgens; after her adrenalectomy, her hormone levels normalized and symptoms improved, illustrating the link between genetic syndromes and endocrine disorders.

This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.

This review discusses rare and controversial conditions like painful nocturnal erections and post-finasteride syndrome, calling attention to these issues but providing no new clinical findings.

This review discusses sex differences in Parkinson's disease and highlights that while men are more frequently affected, androgen-modulating treatments have not yet proven effective for PD, though 5α-reductase inhibitors show potential for further study.

Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.

In this study, researchers found that finasteride exhibits a solid-solid phase relationship that is enantiotropic at normal pressure and becomes monotropic at higher pressure.

This study observed that higher childhood levels of DHEAS were associated with more advanced pubertal development and correlated with changes in DNA methylation near puberty-related genes in both boys and girls, potentially explaining the hormone's influence on puberty.

This study found that the 5α-steroid metabolite profile in men with inherited 5α-reductase deficiency is similar to those taking the drug finasteride, suggesting the gene affects multiple steroid substrates.

This qualitative study revealed that women with PCOS often see themselves as less feminine, affected by symptoms like excess hair and irregular menstruation, which challenged their gender roles.

This review discusses the psychological impacts of androgenetic alopecia on body image and the importance of addressing these issues in hair transplantation patients, without reporting new clinical findings.

This review discusses the portrayal and enforcement of idealized masculinities in men's self-improvement advertising and reports no new empirical results.

This study found that women with PCOS reported significant appearance-related distress and social anxiety, especially in social settings.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

This review discusses the role of genetic mutations and environmental endocrine disruptors in insufficient androgen action, which can result in conditions like hypospadias, cryptorchidism, and micropenis, during male fetal development.

This study found that etifoxine pretreatment reduced neuroinflammation and improved cognitive function in LPS-induced neuroinflammation in mice, potentially through increased neurosteroid synthesis and reduced apoptosis.

This study found that nonobese women with idiopathic hirsutism exhibited lower nitrite/nitrate concentrations and higher fibrinogen levels compared to control subjects, but these were similar to levels in women with polycystic ovary syndrome.