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Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

This case study reports that low-dose testosterone therapy improved libido and sexual functions in a 36-year-old fragile X carrier female with hypoactive sexual desire disorder when monitored regularly for lab parameters.

This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.

This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.

This review examines psychosomatic hair diseases, discussing their classification, implications, and the need for tailored psychosomatic therapy, without reporting new clinical results.

This paper discusses the first reported case of post-finasteride syndrome in a long-term dermatotrichology setting, occurring in a 25-year-old male after dutasteride treatment, and highlights possible links to mental health disorders.

This chapter reviews the biology and biochemistry of hormones involved in male sexual development and physiology, without reporting new research findings.

This updated guideline from the Endocrine Society highlights the importance of endocrinologists in providing safe and effective hormone regimens for gender-affirming care, especially for adolescents who have entered puberty.

This study reviewed research on the psychosocial effects of gender-affirming dermatology treatments in transgender populations, finding mostly positive associations but noting significant limitations and the need for more comprehensive studies to clearly understand these effects.

This source highlights the essential role of androgens in women's health, noting their impact on various body systems and the critical need for more research on androgen therapies regarding side effects, patient selection, and laboratory standardization.

This review discusses the potential risks of ejaculatory dysfunction associated with both medical and surgical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia and their implications for male fertility, but it reports no new clinical results.

This study found that blocking androgen receptors in male rats during the perinatal period led to permanently increased estrogen and ER-a expression in the hypothalamus, affecting sexual preference in adulthood.

This review discusses the crucial role of sex hormones in maintaining and influencing skin health, suggesting ongoing research into hormonal treatments for skin conditions due to life stage changes.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

This article discusses the potential connection between persistent sexual dysfunction and depression in finasteride users for male pattern hair loss, concluding that further research is needed to determine its significance.

This article reviews the reported sexual and psychological side effects of 5-alpha reductase inhibitors for benign prostatic hyperplasia, emphasizing the need for further clinical studies.

This study found that family support significantly predicted improved body image satisfaction and self-esteem among women with PCOS, emphasizing its importance in psychological well-being.

This study proposed a detailed classification of psychodermatosis by examining three cases that illustrate the interaction between the brain and skin, resulting in conditions like trichotillomania and factitious dermatitis.

In this study, females with 5 alpha-reductase-2 deficiency exhibited decreased body hair, normal sebum production, and delayed menarche, suggesting a role for DHT in hair growth and menstrual function.

This study identified significant correlations between self-esteem, psychiatric symptoms, and health-related quality of life in peritoneal dialysis patients.

Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.

This review discusses the complex effects of testosterone on the brain, emphasizing sex differences, and reports no clinical results; the authors highlight the inconsistencies in current study findings.

Finasteride and dutasteride increase sexual dysfunction reports.

In this study, perinatal androgen deprivation in male rats led to elevated estrogen levels and a lack of sexual motivation towards gonadally-intact female rats.

This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.

This study found that chronic exposure to fadrozole or finasteride during frog development induced intersex individuals, which displayed different gene expression profiles depending on the chemical used.

This study observed that overexpressing TSPO in the hippocampal dentate gyrus of mice led to significant anxiolytic and antidepressant-like effects, potentially mediated by increased allopregnanolone synthesis.

This study found that finasteride increased fetal arousal activity in late gestation sheep by suppressing pregnane steroid synthesis, suggesting reduced GABAA receptor-mediated inhibition.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

In this study, researchers observed that acute stress increased levels of the enzyme 5αR2 in the medial prefrontal cortex of male rats, affecting stress reactivity, but this effect was not seen in females.