Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.

This review highlights recent advances in ultrasound-based radiomics and radiogenomics for ovarian cancer, suggesting these techniques improve diagnostic accuracy and patient-specific treatment strategies, despite ongoing challenges with standardization and model interpretability.

This study suggests that IL-1β may play a role in inflammatory signaling pathways in papulopustular rosacea, contributing to its pathogenesis.

This paper reviews the advancements and applications of single-cell transcriptomics in animal research, highlighting its potential to enhance understanding of animal nutrition, health, genetics, and disease models.

This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.

OMICS International promotes scientific research and knowledge sharing by publishing peer-reviewed articles in various fields and organizing international scientific conferences.

In this study, researchers analyzed miRNA and gene expression in the hair follicles of FMD during different hair cycle stages, identifying differential expression patterns and key pathways involved in hair follicle development and growth.

New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.

This review discusses the potential of extracellular vesicles as cell-free tools in tissue engineering and regenerative medicine, noting their emerging role in promoting tissue repair without the risk of host rejection.

This review highlights that Tremella fuciformis polysaccharide exhibits various bioactivities, such as antioxidant and immune-modulating effects, and explores its potential applications in food, pharmaceutical, and cosmetic industries.

This source discusses drug repurposing, which seeks new therapeutic uses for existing drugs, emphasizing its benefits like faster development, reduced costs, and novel treatments for unmet medical needs. The chapter outlines current trends and future perspectives in drug discovery through repurposed drugs.

This review highlights the ongoing challenges and advancements in developing precise and early intervention strategies for autoimmune diseases and emphasizes the need for more personalized and disease-specific therapies.

This article discusses drug repurposing as a strategy to find new uses for existing medications, highlighting its potential benefits like faster development and lower costs, while also addressing challenges such as drug specificity, ethical concerns, and regulatory issues.

This review discusses the potential applications and advantages of encapsulating single cells for use in therapeutics and diagnostics, while also evaluating various methods for effectively creating and sorting single-cell units despite challenges in production and cost.

This review highlights the need for improved methods in cosmetic safety assessment, emphasizing the potential of engineered skin tissue for more effective detection and toxicological evaluation of cosmetic products, compared to traditional methods.

This study found that biliverdin beta and delta, metabolites of heme, play a critical role in Pseudomonas aeruginosa iron acquisition and cooperative behaviors, which are crucial for the bacterium's long-term infection in cystic fibrosis patients, suggesting potential targets for new therapies.

This review discusses various strategies for drug repurposing in tuberculosis treatment, highlighting significant potential but reports no new clinical results.

Genetic studies on hair traits can improve understanding of health and disease.

This review highlights the potential of microalgae as sustainable sources for nutraceuticals and cosmeceuticals, emphasizing their applications in functional foods, dietary supplements, and cosmetics for roles such as anti-aging and photoprotection in alignment with sustainability principles.

This study found that integrating machine learning enhances the predictive accuracy of forensic DNA phenotyping from low template DNA, achieving high accuracy for traits like eye color, although challenges remain for admixed populations and complex traits.

This study found that in cashmere goats, melatonin treatments enhanced cashmere growth by stimulating secondary hair follicles, increasing follicle density, and improving yield and quality, highlighting key genes and metabolic pathways involved in this process.

This review explores the potential of regenerative cosmetics, specifically engineered skin tissues, for rejuvenating aging skin, healing wounds, and restoring hair, offering promising alternatives to traditional dermocosmetic treatments by promoting collagen production, reducing wrinkles, and regenerating hair follicles.

This review discusses the advancements in biologic skin substitutes for wound treatment and their potential in enhancing cutaneous regeneration but reports no new clinical results.

This review highlights the limited effectiveness of current unlicensed treatments for male subfertility, like hormonal therapy and antioxidants, and emphasizes new drug discovery methods such as high-throughput screening and drug repurposing to improve treatment development for male subfertility.

This study identified three new genetic loci linked to sweat gland density in a GWAS involving 6,210 Han Chinese individuals, highlighting potential targets for understanding conditions like anhidrosis and hyperhidrosis and emphasizing the use of quantitative traits in genetic dermatology research.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.

In this study, the researchers observed that biotin administration in biotin-deficient children with alopecia eliminated certain membrane proteins from their blood, suggesting that biotin might regulate these proteins' expression.

This study found that dutasteride reduced β-amyloid plaque load in a cerebral amyloidosis model, seemingly linked to mitochondrial apoptosis and autophagy processes.

This review discusses PRP therapy's history, mechanisms, and innovations in its use across various medical fields, but provides no new clinical results; the authors highlight challenges like standardization and regulatory issues.