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In this study, researchers discussed how specific protein interactions in reptile skin allow for the development of protective structures like scales and scutes, which facilitated reptiles' adaptation to terrestrial environments.

Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.

In this study, researchers found that overexpression of the hairless protein in Hr mutant mice disrupts inner root sheath formation by downregulating Dlx3 and associated keratins in hair follicle development.

In this study, researchers identified 47 proteins associated with male pattern baldness severity and prioritized five candidate genes, including druggable CD38, suggesting new non-hormonal targets for therapeutic development.

This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.

This study found that Myc activation in mouse epidermis impairs keratinocyte adhesion and motility by downregulating extracellular matrix and cytoskeleton proteins, affecting hair lineage differentiation.

This study identifies the PI4P-RHD4 module as a key regulator of GET pathway receptor dynamics in Arabidopsis, affecting TA protein insertion and root hair growth.

This study found that Golvatinib, Gliquidone, and Dihydroergotamine may inhibit the binding of SARS-CoV-2's Nsp1 protein to the host ribosomal subunit, suggesting potential as treatments against COVID-19 variants.

This study established an animal model using UV-irradiated C57BL/6 mice to assess hair luster, reporting that UV exposure alters keratin-associated protein gene expression, and suggested potential for developing effective hair care products by evaluating treatments like oral minoxidil.

Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.

This study found that clusters of mRNAs and lncRNAs in the peripheral blood of PCOS patients were aberrantly expressed, and certain lncRNA-mRNA pairs in the chemokine signaling pathway may be genetically related to PCOS.

This study reports that variation in the ovine TCHH gene may influence wool fibre curvature, with specific gene variants affecting the mean fibre curvature in sheep.

This study found that the unique functions of keratin 16 are likely determined by its tail domain, challenging the previous hypothesis about the role of the helix 1B subdomain.

This study used single-cell techniques and lineage tracing to reveal that integrin α6 expression in neural crest cells can differentiate them into Schwann cells, melanocytes, and fibroblasts in skin, identifying integrin α6 as a potential marker for these derivatives.

This study integrated single-cell RNA-seq data from four previous studies to create a comprehensive human corneal cell state meta-atlas, revealing novel marker genes, rare cell states, and distinct transcription factors, and offering a tool to enhance future cornea research.

CaBP1 and 2 are important for maintaining the activity of calcium channels necessary for hearing in inner ear cells.

This study concluded that MEX3A is critical for maintaining Lgr5+ intestinal stem cells by regulating the PPARγ pathway, impacting intestinal homeostasis during postnatal development in mice.

This review discusses the roles of the transcription factor SOX9 in organ development and maintenance, providing insights into its regulation and diverse functions, but reports no new experimental results.

This study found that UC.145 influences DKK1 methylation and Wnt signaling in gastric cancer, with implications for patient survival and its potential as a predictive biomarker.

This study identified multiple genetic variants in Pakistani families with oculocutaneous albinism, including two novel variants, enhancing understanding of its genetic basis and aiding better management and counseling.

This article discusses intra-host single-nucleotide variants in SARS-CoV-2, highlighting their potential to inform on virus strain diversity, immune escape, and drug design, but it reports no new clinical results.

This study found that STAT3 directly inhibited the activity of the sheep FST gene promoter, consequently reducing cell proliferation and promoting a better understanding of hair follicle development mechanisms.

This study found that both natural and environmental selection have significantly influenced the goat genome, revealing genetic loci tied to adaptation, fitness, and productive traits, more so than artificial selection, across various goat populations.

This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.

This study introduces scINSIGHT, a method that showed improved performance over existing approaches in identifying gene expression patterns and cellular processes in heterogeneous scRNA-seq datasets from different biological conditions.

In this study on Chinese Tan sheep, researchers discovered a variant of the KRTAP19-5 gene associated with decreased curvature of fine wool fibres, highlighting potential genetic markers for improving wool quality.

This study found that the lncRNA lncRNA2919 is involved in hair follicle regeneration by downregulating growth-related genes, inhibiting cell proliferation, and promoting apoptosis in rabbit dermal papilla cells.

This study found that desmocollin 1 is crucial for strong adhesion and barrier maintenance in the mouse epidermis, with its absence leading to skin and hair issues resembling chronic dermatitis.

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.

Among Merino × Southdown cross sheep, this study found that certain variants of the KRT81 gene were associated with differences in fleece weight, but not with staple length or fibre diameter traits.