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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Human skin can make serotonin and melatonin.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Different types of skin cells play specific roles in development, healing, and cancer.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Androgens can both increase and decrease hair growth in different parts of the body.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Lactate production is important for activating hair growth stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.