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This article reviews the mechanism, use, and alternatives for finasteride in dermatology and provides no new clinical results.

This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.

This study found that BAMO acupuncture combined with Simiao pill can help restore normal prostate tissue structure in mice by reducing DHT production, promoting apoptosis, and decreasing inflammatory responses.

This study found that components derived from Uromedic® pumpkin seeds, especially Δ7-sterols, may inhibit DHT production and AR binding, potentially benefiting prostate and bladder health by moderating these mechanisms.

Finasteride reduces melanin production in skin cells.

Finasteride reduces prostate size and symptoms with few side effects.

This study found that finasteride decreased DHT-stimulated AR activity and cell growth in prostate cancer cells with mutant AR, but not in those with wild type AR.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

This review discusses the molecular mechanisms of masculinization involving androgen signaling and their roles in male embryonic development and conditions like hypospadias and prostate cancer, and reports no clinical results.

In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.

This research suggests that the enzyme Phospholipase D from E. coli is a strong candidate as the underlying cause of benign prostatic hyperplasia, potentially mediated by its conversion to lysophosphatidic acid in the prostate.

This study found that tailored treatments based on urodynamic testing improved urinary bladder dysfunction in Parkinson's disease patients, thereby enhancing their quality of life and protecting kidney function.

This study found that finasteride significantly alters urinary steroid profiles, complicating the detection of steroid abuse in doping-control analysis by potentially causing false-negative results.

This study developed a pharmacokinetic/pharmacodynamic model for finasteride, concluding that finasteride's nonlinear pharmacokinetics are likely due to its saturable binding to 5alphaR2.

This article reviews the use of 5alpha-reductase inhibitors for managing benign prostatic hyperplasia and reports no new clinical results.

This review discusses the roles of dihydrotestosterone in fetal development and adult diseases, reporting no new clinical results; the authors emphasize the potential of 5α-reductase inhibitors for treatment.

This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.

This review discusses the development and potential therapeutic applications of steroid sulfatase inhibitors for hormone-dependent disorders and cognitive dysfunction, reporting no new clinical results.

This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.

This review discusses the complex relationship between melasma and factors like female sex hormones, genetics, and ultraviolet light exposure, but reports no new clinical findings.

In this study, osthenol was identified as a highly potent inhibitor of 5alpha-reductase type I in LNCaP cells, significantly outperforming finasteride.

In this review, the role of DHT in male-type obesity and metabolic diseases is discussed, with increased levels potentially exacerbating cardiovascular disease risk; the paper reports no new results.

This article reviews the impact of aging and related urologic conditions on male fertility, highlighting the effects of various treatments on sperm parameters and recommending pre-treatment counseling for fertility preservation. It reports no new clinical results.

This review discusses the expression of PSA in hormonally-regulated tissues and female malignancies, emphasizing its potential as a diagnostic biomarker and role in antidoping initiatives.

This study found that PSA concentrations in peripheral blood are related to androgen levels, suggesting that PSA is a valuable marker for diagnosing hyperandrogenism in women.

In this case report, the researchers emphasize the importance of regular prostate exams and PSA tests for diabetic men, including those who are hypogonadal, because prostate cancer development is linked to intraprostatic dihydrotestosterone levels, not serum testosterone levels.

This article discusses the hypothesis that mechanisms driving androgenic alopecia may reduce the risk and proliferation of prostate cancer by increasing prostaglandin D2 levels but presents no new clinical findings.

This study identified pantolactam based compounds as effective topical antagonists of the androgen receptor, reducing sebum components in a hamster model.

This article discusses the role of dihydrotestosterone in human prostatic adenocarcinoma growth and suggests that 6-methyleneprogesterone could be used to inhibit DHT for treating hormone-responsive prostate cancer, without new clinical findings.

This review discusses the hormonal influences on prostate carcinogenesis and notes ongoing trials investigating whether finasteride could reduce prostate cancer incidence by inhibiting dihydrotestosterone synthesis, but it reports no new results.