The Visitors of the Sick

    November 2011 in “ Nature Clinical Practice Urology ”
    Doyenné de Ciney
    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Studysummary This article reviews the use of 5alpha-reductase inhibitors for managing benign prostatic hyperplasia and reports no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.
    Benign prostatic hyperplasia (BPH) was a common issue among older men, characterized by an enlarged prostate and urinary symptoms, potentially leading to complications like acute urinary retention (AUR) or surgery. Dihydrotestosterone played a key role in prostate growth, and 5alpha-reductase inhibitors (5ARIs) such as dutasteride and finasteride were used to treat BPH by inhibiting this hormone's production. These medications were effective in reducing prostate volume, improving urinary flow, alleviating symptoms, and decreasing the risk of AUR and surgery. 5ARIs were the only medical therapy available at the time that could prevent disease progression and provide long-term symptom control, making them essential for men with enlarged prostates at risk of progression.
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