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    Did you mean 5-alpha-reductase inhibitor?
    Glossary 5-alpha-reductase inhibitor

    blocks enzyme converting testosterone to dihydrotestosterone (DHT)

    A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

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    Research 10 of 1000+

    1. DIHYDROTESTOSTERONE AND THE PROSTATE: THE SCIENTIFIC RATIONALE FOR 5α-REDUCTASE INHIBITORS IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA 2004 · 235 citations
    2. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    3. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    4. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    5. Long-term use of 5α-reductase inhibitors and the risk of male breast cancer Cancer Causes & Control · 2014 · 28 citations
    6. 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction Neurobiology of Disease · 2018 · 26 citations
    7. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    8. 5alpha-reductase inhibitors - a new hope in dermatology? International Journal of Dermatology · 1997 · 15 citations
    9. Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors Chemical and Pharmaceutical Bulletin · 2005 · 13 citations
    10. Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction. PubMed · 2012 · 13 citations
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    Community 10 of 251

    1. BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside) Reddit · 10 Jun 2025
    2. Why does this industry still revolve around 5-AR inhibitors? Reddit · 14 Jun 2021
    3. Similar 5ar inhibitors to fin? Reddit · 26 Jun 2021
    4. [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors? Reddit · 22 Mar 2026
    5. Guys if you can’t take 5AR inhibitors still get on treatment ASAP Reddit · 6 Jan 2026
    6. 1 year 5-ar. Blood test results Reddit · 29 Jul 2025
    7. Meta analysis of minoxidil only vs 5AR inhibitors Reddit · 16 May 2025
    8. Can gains from stemoxydine be permanently kept with 5AR inhibitors? Reddit · 29 Dec 2024
    9. FINALLY stopped shedding constantly after 1 year on 5ar inhibitors!! Moral of the story: Just wait Reddit · 15 Oct 2024
    10. Allopregnanolone deficiency by 5-ari inhibition (fin/dut users) Reddit · 11 Dec 2023
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    Learn 3 of 6

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Neem Oil Oil from the neem tree, used in traditional remedies
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