September 2020 in “Scientific periodicals of Ukraine” This study found that the combination therapy of Flosin and Prostamol Uno over nine years was well tolerated and equally effective in managing benign prostatic hyperplasia symptoms as the combination of doxazosin and finasteride, with fewer adverse events reported.
2 citations
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April 2014 in “PubMed” Platelet Rich Plasma (PRP) shows promise for hair growth, ulcer healing, and skin rejuvenation, but more research is needed for consistent results and it's not suitable for people with certain blood conditions.
September 2023 in “International Journal of Science and Research (IJSR)” In this case study, PRP and PRF treatments helped achieve complete healing of chronic wounds, including a chemical burn ulcer in three weeks and a pilonidal sinus post-incision in eight weeks, suggesting potential benefits for chronic wound management.
April 2023 in “IntechOpen eBooks” This review discusses neuropathic pruritus, detailing its clinical presentations and management strategies, but reports no new clinical results.
This study found that platelet-rich plasma improved the development and maturation of the skin and hair follicles in neonatal mice compared to a saline control.
March 2024 in “Journal of Neuroscience Research” In this study, researchers found that repeated finasteride administration in female rats led to antidepressant- and anxiolytic-like effects, potentially linked to increased estradiol and decreased corticosterone levels, with implications for neurosteroid-based treatments in women.
February 2026 in “Frontiers in Pharmacology” This study found that injecting PRP gel derived from a patient's own blood may promote tissue regeneration and closure of intestinal fistulas unresponsive to conservative therapy.
44 citations
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February 2009 in “Pain” This study found that progesterone can inhibit spinal reflex potentiation in ovariectomized rats through GABA(A) receptor activity, mediated by neurosteroid metabolism rather than direct progesterone receptor action.
22 citations
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January 2018 in “European urology focus” This review discusses recent advancements and new approvals in the medical treatment of lower urinary tract symptoms, particularly highlighting drugs for nocturia and ongoing trials for multiple related conditions, while reporting no new clinical results.
May 2022 in “The Egyptian Journal of Hospital Medicine” This review discusses the role of platelet-rich plasma in dermatological treatments and reports no new clinical results, indicating its increasing use among dermatologists.
January 2018 in “Urologe A” In this case report, botulinum neurotoxin injections were associated with a 6-month cessation of priapism episodes in a young man with recurring low-flow priapism, following unsuccessful conventional treatments.
2 citations
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January 2012 in “Journal of The Chilean Chemical Society” This study developed and validated a precise RP-HPLC-PDA method for estimating finasteride in bulk and tablet forms, suitable for quality control use.
November 2017 in “Journal of Evolution of Medical and Dental Sciences” This study found that in a specific setup, the syringe method of platelet-rich plasma preparation was more effective for platelet increment and sterility compared to the tube method.
March 2026 in “The Aging Male” This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.
5 citations
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January 2018 in “PubMed” In this study, applying a biodegradable microneedle patch after topical steroid application significantly increased steroid penetration and improved treatment outcomes in patients with prurigo nodularis compared to the control.
August 2024 in “Journal of Clinical Medicine” This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.
PRP can help regrow hair and improve hair transplant results.
In this study, Paljeong-san pharmacopuncture reduced dihydrotestosterone levels and inhibited prostate tissue proliferation in a rat model of benign prostatic hyperplasia.
4 citations
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July 2024 in “European Archives of Oto-Rhino-Laryngology” This study found that platelet-rich plasma injections significantly improved olfactory function in patients with long-lasting postviral olfactory dysfunction, suggesting potential as a therapeutic strategy.
3 citations
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May 2024 in “Frontiers in Physiology” In this study, male rats with spinal cord injury that received either E2 or DHT supplementation both showed restored expression of respiratory neuroplasticity following acute intermittent hypoxia, with E2 also enhancing overall breathing recovery.
September 2017 in “Springer eBooks” PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This policy brief highlights that post-drug syndromes remain under-recognized in pharmacovigilance, leading to inadequate risk assessments and patient care. It identifies systemic failures in current frameworks and recommends actions to improve long-term drug safety monitoring and education, affecting public health outcomes significantly.
November 2025 in “Advanced Therapeutics” This review examines platelet-rich plasma therapy's multidisciplinary applications in regenerative medicine and discusses preparation challenges but presents no new clinical results.
July 2025 in “Dermatologic Surgery” This study found that PRP may increase hair density in breast cancer survivors with EIA or pCIA, but improvements did not differ statistically between treated and untreated sides.
September 2025 in “Journal of Neonatal Surgery” This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair loss in patients with androgenetic alopecia over six months, but lacks a comparative placebo or alternative treatment group.
6 citations
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October 2012 in “Pediatrics” This case report describes an 11-year-old girl who experienced hot flashes and menarche after taking a Serenoa repens supplement for telogen effluvium, suggesting a possible but uncertain link between the supplement and hormonal changes.
August 2024 in “Medicine” This study found that medroxyprogesterone acetate and ethinyl estradiol with drospirenone were the most frequently prescribed medications for PCOS, with some patients experiencing drug changes or discontinuation due to side effects or therapeutic failure.
August 2021 in “Journal of Pakistan Association of Dermatologists” This study found that cutaneous manifestations in patients undergoing hemodialysis are common and often worsen with longer treatment duration.