Rapid Analysis of Finasteride in Bulk and Formulations by RP-HPLC-PDA Method

January 2012 in “ Journal of The Chilean Chemical Society ”

Sindhura Manne, Raghavi Kakarla, Prashanth Iraavi, Buchi N. Nalluri

TLDR New method accurately measures finasteride in tablets and bulk.

The paper presents a validated method for analyzing finasteride in bulk and tablet formulations using RP-HPLC-PDA. The method was found to be accurate, sensitive, and specific, with good recovery of the added standard to the drug product sample. The proposed method is highly sensitive, reproducible, reliable, rapid, and specific and can be employed in quality control to estimate the amount of finasteride in bulk and in dosage forms.

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Research cited in this study

3 / 3 results

research A New Spectrophotometric Method for the Determination of Finasteride in Tablets

22 citations, July 2007 in “Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy”

New method accurately measures finasteride in tablets.

research Determination of Finasteride in Tablets by High Performance Liquid Chromatography

13 citations, January 2007 in “E-journal of Chemistry”

Found accurate way to measure finasteride in tablets.

research Separation of Finasteride and Analogues

11 citations, November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Finasteride and analogues separated using LC-MS-MS technique.

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research High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses

19 citations, May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Reliable method detects finasteride in human plasma at low doses.