A New Spectrophotometric Method for the Determination of Finasteride in Tablets

September 2006 in “ Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy ”

Sevgi Tatar Ulu

Studysummary This study describes a new colorimetric method for accurately and precisely measuring finasteride in tablets, with results comparable to the standard HPLC method. Our plain-language summary of this paper — not a Tressless recommendation.

This study proposes a new method for determining the concentration of finasteride in tablets using spectrophotometry. The method was found to be accurate, precise, and sensitive, with good recovery values. The proposed method can be applied for the determination of individual compounds in a multi-component mixture and is suitable for routine quality control. The study concludes that the proposed method is advantageous over other reported visible spectrophotometric and colorimetric methods.

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research Development and Validation of a New Gas Flame Ionization Detector Method for the Determination of Finasteride in Tablets

13 citations , February 2006 in “Analytical Biochemistry”

This study reported a simple and validated gas chromatography method to accurately measure finasteride in tablets, showing equivalency to the official method with no significant differences.

research Polarographic Behavior and Determination of Finasteride

21 citations , February 2003 in “Farmaco”

Method quickly measures finasteride concentration in capsules.

research A Stability-Indicating HPLC Method to Determine Finasteride in a Tablet Formulation

19 citations , December 2002 in “Journal of Liquid Chromatography & Related Technologies”

This study developed and validated a high-performance liquid chromatographic method for identifying finasteride and its degradation products, showing excellent resolution and sensitivity under various decomposition conditions.

research LC Determination of Finasteride and Its Application to Storage Stability Studies

27 citations , July 2001 in “Journal of Pharmaceutical and Biomedical Analysis”

Finasteride remains stable for two years with proper storage.

research Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography

24 citations , February 2000 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Valid method measures finasteride in plasma, simple, fast, and affordable.

research Finasteride

40 citations , April 1999 in “Drugs”

This study concluded that finasteride is a viable first-line treatment for moderate uncomplicated benign prostatic hyperplasia, particularly in patients with larger prostates, by significantly reducing acute urinary retention and the need for surgery.

research Finasteride

125 citations , January 1999 in “Drugs”

This study found that oral finasteride 1 mg/day promotes hair growth and prevents further hair loss in a significant proportion of men with male pattern hair loss over two years.

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

823 citations , February 1998 in “Analytical Chemistry”

Method detects finasteride in plasma at very low concentrations.

Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography

research Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography

17 citations , May 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Method accurately measures finasteride in human plasma.

High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching

research High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching

29 citations , February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications”

This study developed a fully automated HPLC method for accurately quantifying finasteride in human plasma, achieving a detection limit of 1 ng/ml with validated application in pharmacokinetic studies.

Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method

research Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method

20 citations , December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry

research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry

45 citations , August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Method detects finasteride in plasma and semen with high sensitivity and accuracy.