Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Randomized, Controlled, Pilot Study

    July 2025 in “ Dermatologic Surgery
    Anthony Rossi, Alexander Pan, Christian Menzer, Leore Lavin, Saud Aleissa, Abdullah Aleisa, Hesham Alshaikh, George Dranitsaris, Stephen W. Dusza, Cindy Bravo, Mario E. Lacouture
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    TLDR PRP may increase hair density but doesn't improve quality of life in breast cancer survivors with hair loss.
    This study investigated the safety and efficacy of platelet-rich plasma (PRP) treatment for endocrine-induced alopecia (EIA) and persistent chemotherapy-induced alopecia (pCIA) in breast cancer survivors. Conducted as a single-center, randomized, controlled trial, it involved 15 EIA and 12 pCIA patients who received PRP injections on one side of their scalp monthly for 3 months. Results showed an improvement in the global assessment scale (GAS) from baseline to week 12, with hair density increasing on both treated and untreated sides. However, there was no significant difference between the sides, and quality of life did not improve. Adverse events included mild to moderate scalp pain, and no adverse cancer outcomes or tumor seeding were observed. The study suggests PRP may increase hair density, but results could be influenced by PRP diffusion in the split-scalp design.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 8 months ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  6 upvotes 1 year ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 1 year ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

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