95 citations,
February 2019 in “The New England Journal of Medicine” Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.
62 citations,
March 2012 in “Journal of the European Academy of Dermatology and Venereology” Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.
37 citations,
August 2016 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.
25 citations,
September 2010 in “Journal of Cutaneous Medicine and Surgery” The study found that Central Centrifugal Cicatricial Alopecia mainly affects middle-aged African descent women, is linked to certain hair care practices and genetics, and often goes undiagnosed for years.
22 citations,
October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
14 citations,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
11 citations,
January 2009 in “Acta Dermato Venereologica” Early and aggressive treatment can significantly regrow hair in discoid lupus erythematosus.
4 citations,
May 2021 in “Biomedicines” Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
3 citations,
November 2019 in “The American Journal of Dermatopathology” Widened sweat ducts are a very specific sign of scarring hair loss.
2 citations,
April 2022 in “Clinical, cosmetic and investigational dermatology” A new plant-based treatment was effective for hair regrowth in women with a specific type of hair loss that didn't respond to usual treatments.
February 2024 in “International journal of medical science and clinical research studies” CCCA is a scarring hair disorder mainly affecting people of African descent, needing better awareness and treatment.
12 citations,
June 2020 in “Dermatology and therapy” Platelet-Rich Plasma (PRP) can promote new hair growth and increase hair density, but its effectiveness varies depending on the type of hair loss.
1 citations,
October 2021 in “Cosmoderma” Hair transplants can work for permanent hair loss if the condition is stable and done carefully.
4 citations,
May 2012 in “Journal of Investigative Dermatology” The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.
April 2020 in “The Egyptian Journal of Plastic and Reconstructive Surgery” Both follicular unit extraction and scalp expanders effectively treat secondary cicatricial alopecia, with scalp expanders leading to quicker and denser hair growth.
January 2018 in “Journal of clinical and investigative dermatology” Dermoscopy is a useful, low-cost method for diagnosing various types of hair loss disorders known as Cicatricial Alopecia.
March 2022 in “JAAD case reports” Accurate diagnosis is crucial for effective treatment of hair loss.
16 citations,
January 2011 in “Indian Journal of Dermatology” Most patients with cicatricial alopecias face significant psychological and social challenges due to their hair loss.
1 citations,
August 2022 in “JAAD case reports” Pioglitazone use was linked to hair regrowth in a patient with permanent hair loss from cicatricial alopecia.
1 citations,
November 2017 in “International Journal of Research in Medical Sciences” Dermoscopy helps distinguish between scarring and non-scarring hair loss and accurately diagnoses hair and scalp conditions without needing hair plucking.
1 citations,
November 2016 in “International Journal of Research in Dermatology” The study found no significant link between the symptoms, tissue analysis, and immunofluorescence results in scarring hair loss conditions.
September 2023 in “International journal of women’s dermatology” Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.
1 citations,
July 2017 in “Skin Appendage Disorders” A woman developed permanent hair loss after a face-lift surgery despite various treatments.
170 citations,
December 2009 in “Histopathology” The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
56 citations,
January 2019 in “Skin appendage disorders” The most common hair loss type at specialist clinics is androgenetic alopecia, especially in younger men, followed by alopecia areata and telogen effluvium, with differences seen across regions.
37 citations,
June 2011 in “Journal of The American Academy of Dermatology” Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.
26 citations,
January 2016 in “Journal of cutaneous and aesthetic surgery” Hair transplant combining scalp and beard hair with PRP was successful for scarring alopecia.
9 citations,
November 2009 in “Journal of the European Academy of Dermatology and Venereology” Cutting scalp biopsies in consecutive slices improves diagnosis of hair loss conditions.
7 citations,
January 2013 in “Journal of Investigative Dermatology” Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.