Trichoscopic Findings in Cicatricial Alopecias and Hair Shaft Disorders and Its Application in Histopathology

    Ashwini Khadatkar, Nishant Ghodake
    Image of study
    TLDR Dermoscopy helps distinguish between scarring and non-scarring hair loss and accurately diagnoses hair and scalp conditions without needing hair plucking.
    The study conducted between August 2014 to June 2016 at the Dermatology outpatient department, Skinaccess clinics, Nashik, focused on the dermoscopic patterns of various cicatricial alopecias in Indian skin types IV and V. The most common and characteristic feature observed in all 24 patients with cicatricial alopecia was hair follicle effacement. Other findings included hair follicle plugging in 25% of patients with Discoid Lupus Erythematosus (DLE) and one patient with idiopathic scarring, hyperkeratotic perifollicular scaling in patients with lichen plano pilaris, and patchy depigmentation in patients with DLE, idiopathic scarring, and lichen plano pilaris. The study concluded that dermoscopy is useful in differentiating cicatricial from non-cicatricial alopecias, and dermoscopic guided biopsies yielded definitive pathological diagnosis in 95% of the cases. Hair shaft disorders could be easily diagnosed by dermoscopy, eliminating the need for hair plucking.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 14 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Comprehensive Microneedling Guide

      in Microneedling  289 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

    Similar Research

    5 / 1000+ results
      Cicatricial Alopecia: Overview and Treatment Options

      research Cicatricial Alopecia: Overview and Treatment Options

      1 citations, October 2018 in “InTech eBooks”
      The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
      Autoimmune Disease and Hair Loss

      research Autoimmune Disease and Hair Loss

      35 citations, October 2012 in “Dermatologic Clinics”
      Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.
      Skin Biopsy

      research Skin Biopsy

      106 citations, December 2015 in “Journal of The American Academy of Dermatology”
      Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.
      Hair Transplantation in Cicatricial Alopecias

      research Hair Transplantation in Cicatricial Alopecias

      2 citations, January 2013 in “Hair therapy & transplantation”
      Hair transplants can be a treatment for scarring hair loss if there's good blood flow and no active disease.