Follicular Unit Transplantation Versus Scalp Expansion in Management of Secondary Cicatricial Alopecia

    Amr Ads, Mahmoud Abdel Nabi Saeed, Ahmed Abo Hashem Azzab Moossa, Mohamed Hassan Abdel Aal
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    TLDR Both follicular unit extraction and scalp expanders effectively treat secondary cicatricial alopecia, with scalp expanders leading to quicker and denser hair growth.
    The study conducted in 2020 involved 30 patients suffering from secondary cicatricial alopecia, divided into two groups: 13 underwent follicular unit extraction (FUE) and 17 had scalp expanders (SE). The results showed that the surface area of alopecia was significantly larger in the SE group than the FUE group, with a p-value <0.001. Post-operative recovery was similar in both groups, but the SE group experienced faster hair gain and better hair density. The study concluded that both FUE and SE are effective tools in managing secondary cicatricial alopecia when properly selected and tailored to the patient's needs.
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      community Verteporfin and Microneedling

      in Treatments 6 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

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