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Research

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research Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

665 citations , April 2016 in “Nature communications”

This study shows that inhibiting anti-apoptotic proteins BCL-W and BCL-XL can specifically induce apoptosis in senescent cells, suggesting a potential strategy for treating age-related pathologies.

research Selenium for preventing cancer

618 citations , January 2018 in “Cochrane Database of Systematic Reviews”

This study reported that selenium supplements do not reduce cancer risk and may increase the risk of type 2 diabetes and high-grade prostate cancer, while observational studies suggest mixed associations between selenium exposure and cancer incidence.

Exogenous Testosterone Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum Testosterone

research Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T

506 citations , March 2005 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.

research Acne and sebaceous gland function

463 citations , September 2004 in “Clinics in dermatology”

This review discusses the development, function, and complex roles of sebaceous glands in acne and suggests future acne treatments should target inflammation and lipid production; it reports no new clinical results.

research The Neurobiology of Sexual Function

393 citations , November 2000 in “Archives of General Psychiatry”

This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.

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Community Join

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community Second shed is real guys !!!!!

in Is this regrowth? 134 upvotes 6 months ago

The conversation discusses hair shedding experienced by users on minoxidil and finasteride treatments, with some considering additional options like spironolactone and dutasteride. Many users report experiencing a second shedding phase but are advised to continue treatment as it may lead to thicker hair regrowth.

community Seeing Good Minoxidil + Dutasteride Results! (after finally being diligent!)

15 upvotes 1 day ago

Consistent use of minoxidil and dutasteride significantly improved hair loss. Regular application and strict adherence to the regimen are crucial for seeing results.

community Sergio Ramos (41) btw. Does winning the world cup make you baldness resistant?

828 upvotes 1 month ago

Sergio Ramos is admired for his hair despite playing in the sun for years, with speculation about genetics, hair treatments, or surgeries like finasteride or dutasteride use. The conversation humorously suggests winning the World Cup might make one resistant to baldness.

community Severe shedding and thinning around 1 year after hair transplant — can transplanted hair grow back?

6 upvotes 1 month ago

The user experienced severe hair shedding and thinning about a year after a hair transplant, despite using finasteride and minoxidil. They are concerned about whether the transplanted hair can regrow or if it is miniaturizing.

community Seeing some progress but looking for advice

138 upvotes 1 month ago

The user has been using 1mg oral finasteride and topical minoxidil for a year and is considering switching to dutasteride or adding a derma roller to improve hair thickness. Suggestions include switching to oral minoxidil, adding microneedling, scalp massages, and possibly using a derma pen or tretinoin for better results.

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Learn

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learn Selenium

What is Selenium and why is it important for healthy hair and scalp function? Selenium is essential for hair health due to its antioxidant properties and role in thyroid function.
Can Selenium supplements help prevent or reverse hair loss caused by nutritional deficiencies? Selenium supplements may not effectively prevent or reverse hair loss from nutritional deficiencies.
What are the risks of taking too much Selenium, and how can you get the right amount safely? Excess selenium can cause toxicity; aim for recommended dietary amounts through food sources.

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learn Sea Salt

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learn Centella

Sensitive to hormones? A centella scalp mask may help ease hidden inflamm Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.