Risk Factors and Comorbidities Associated With Central Centrifugal Cicatricial Alopecia

    September 2023 in “ International journal of women’s dermatology ”
    Maxwell Green, Aileen Feschuk, Manuel Valdebran
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    TLDR Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.
    The document reviews 15 studies on Central Centrifugal Cicatricial Alopecia (CCCA), a common form of hair loss primarily affecting Black women aged 30-55. Risk factors for CCCA include type 2 diabetes mellitus, bacterial scalp infection, traction hairstyles, previous pregnancies, use of chemical hair relaxers, and certain hair grooming practices. Comorbidities associated with CCCA include type 2 diabetes mellitus, uterine fibroids, hyperlipidemia, and vitamin D insufficiency/deficiency. However, the results are mixed, with some studies finding no increased risk of comorbidities or no significant difference in rates of depression or anxiety in women with CCCA compared to controls. The document concludes that more research is needed, and that current treatment focuses on anti-inflammatory medications, with potential future use of antifibrotic agents.
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