Clinical Factors and Hair Care Practices Influencing Outcomes in Central Centrifugal Cicatricial Alopecia

    December 2022 in “ Research Square (Research Square) ”
    Toluwalashe Onamusi, Jorge Larrondo, Amy Mcmichael
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    TLDR Certain health conditions and hair care habits affect the treatment results for a scalp condition called Central Centrifugal Cicatricial Alopecia.
    In a study of 100 patients with Central Centrifugal Cicatricial Alopecia (CCCA), it was found that certain clinical factors and hair care practices influenced treatment outcomes over a one-year period. After treatment, 50% of patients' conditions were stable, 36% improved, and 14% worsened. Notably, patients without thyroid disease, those using metformin for diabetes, using hooded dryers, wearing natural hairstyles, and having no other physical signs besides CCCA were more likely to see improvement. Conversely, the presence of scaling or pustules was associated with a higher likelihood of worsening. Those with a history of thyroid disease, not using hooded dryers, or not wearing natural hairstyles were more likely to remain stable. These findings suggest that medical features, concurrent conditions, and hair care practices can significantly impact the clinical outcomes of CCCA treatment, and this information can be used to tailor therapies and evaluations for affected patients.
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