Central Centrifugal Cicatricial Alopecia: An Approach to Diagnosis and Management

    Pamela Summers, Angela Kyei, Wilma F. Bergfeld
    Image of study
    TLDR Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.
    This document from 11 years ago discusses the diagnosis and management of Central Centrifugal Cicatricial Alopecia (CCCA), which is the most common cause of permanent hair loss in African-American women. The article emphasizes the importance of a thorough clinical history, clinical exam, and laboratory evaluations in determining the correct diagnosis. CCCA is a scarring alopecia that clinically resembles non-scarring alopecia, making it challenging to diagnose. The onset and duration of hair loss, grooming history, and gynecological history are important factors to consider. The article also provides a method for the diagnostic process and suggests that cosmetologists may be confounders in this disorder. Treatment options are limited, and the goal is to prevent progression of the disease. The authors recommend anti-inflammatory agents, stress reduction techniques, and discontinuation of damaging hair-grooming practices. Follow-up should occur every 3-4 months.
    Discuss this study in the Community →

    Research cited in this study

    12 / 12 results

    Related Community Posts Join

    6 / 55 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 10 months ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

    Related Research

    7 / 7 results