Dermatoscopic Evaluation of Central Centrifugal Cicatricial Alopecia Beyond the Vertex Scalp

    July 2020 in “ JAMA dermatology
    Kayla Felix, Brianna De Souza, Nataly Portilla, Latrice Hogue, Christine S. Ahn, Omar P. Sangüeza, Amy Mcmichael
    TLDR Dermatoscopy can help diagnose CCCA without visible hair loss, offering a less invasive option than biopsy.
    The study investigated the use of dermatoscopy as a diagnostic tool for Central Centrifugal Cicatricial Alopecia (CCCA) beyond the vertex scalp, particularly in African American individuals. It aimed to determine if dermatoscopic and histopathologic findings could identify CCCA in areas without visible hair loss, suggesting that CCCA might manifest as patchy hair loss beyond the vertex. The study found that dermatoscopy could potentially serve as a less invasive alternative to biopsy for diagnosing subclinical CCCA, highlighting its reliability in detecting the disease even in the absence of clinically active symptoms.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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