Central Centrifugal Cicatricial Alopecia: A Survey of Treatment Practices Among Dermatology Residents and Attending Physicians

    September 2025 in “ Cureus ”
    Janet Choi, Isabelle Ilan, Jinhui Tian … Kseniya Kobets
    Studysummary This study found that dermatologists in an urban academic setting most frequently use topical corticosteroids, intralesional corticosteroids, and topical minoxidil for treating central centrifugal cicatricial alopecia, aligning with current literature recommendations on reducing inflammation.
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    Research cited in this study 13

    1. Systematic Review of Exosome Treatment in Hair Restoration: Preliminary Evidence, Safety, and Future Directions Journal of Cosmetic Dermatology · 2023
    2. Beyond The Hot Comb: Updates In Epidemiology, Pathogenesis, And Treatment Of Central Centrifugal Cicatricial Alopecia From 2011 To 2021 American Journal of Clinical Dermatology · 2022
    3. Platelet-Rich Plasma and Its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review Dermatology and therapy · 2020
    4. Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin JAAD Case Reports · 2020
    5. Topical Ketoconazole for the Treatment of Androgenetic Alopecia: A Systematic Review Dermatologic Therapy · 2019
    6. Premature Desquamation of the Inner Root Sheath in Noninflamed Hair Follicles as a Specific Marker for Central Centrifugal Cicatricial Alopecia The American Journal of Dermatopathology · 2018
    7. Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
    8. Adverse Effects with Finasteride 5 mg/Day for Patterned Hair Loss in Premenopausal Women International Journal of Trichology · 2018
    9. Central Centrifugal Cicatricial Alopecia: Challenges and Solutions Clinical, Cosmetic and Investigational Dermatology · 2016
    10. Pathologic Diagnosis of Central Centrifugal Cicatricial Alopecia on Horizontal Sections American Journal of Dermatopathology · 2014
    11. Medical and Environmental Risk Factors for the Development of Central Centrifugal Cicatricial Alopecia Archives of Dermatology · 2011
    12. Medical and Surgical Therapies for Alopecias in Black Women Dermatologic Therapy · 2004
    13. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004