Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.

This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.

TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.

This study reports that stress-related neurohormones and factors, such as CRH and SP, can inhibit hair growth and alter immune functions in murine and human hair follicles.

This study found that platelet factor 4 in platelet-rich plasma suppresses human hair follicle growth and alters related gene expressions, suggesting potential implications for its use in hair loss treatment.

This study found that substance P and calcitonin-gene-related peptide have different roles in regulating hair growth in mice, with substance P promoting anagen progression and calcitonin-gene-related peptide inhibiting it.

This study found that most potassium channel blockers increased the activity of slowly adapting mechanoreceptors in rat whisker pads, while the opener NS1619 decreased their evoked activity.

This review discusses the roles of several neuropeptides in skin-immune interactions and inflammatory responses, reporting no new results and emphasizing the need for further study in conditions such as psoriasis and dermatitis.

This paper discusses various toxicological properties of diphenyl cresyl phosphate, highlighting its low acute toxicity, potential neurotoxicity linked to o-cresyl phosphate content, and the lack of data for inhalation exposure, but presents no new experimental findings.

This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.

The KDM1 gene helps Venus flytraps close by managing potassium ions.

In this study, topical phenylephrine significantly reduced hair shedding and increased the force needed to pluck hair in women undergoing cosmetic procedures, suggesting its potential utility for traction alopecia.

In this study, researchers found that barrier-enhancing formulations significantly reduced the penetration of proteins into hair follicles in porcine skin models, with effectiveness varying by formulation.

This study found that Substance P increased mitochondrial activity and biogenesis markers in cultured human scalp hair follicles, suggesting a novel link between stress-related neuropeptide signaling and hair follicle mitochondrial responses.

This study suggests that alkaline phosphatase-regulated expression of CCL5 contributes to the trichogenicity of human dermal papilla spheres.

Loss of Dsc3 function in the epidermis impaired cell adhesion, leading to blistering and hair loss, which suggests a potential cause of PV-like skin diseases according to this study.

Chicken feather gene mutation helps understand human hair disorders.

This study found that the LEF-1 binding site acts as an enhancer element for the wool keratin intermediate filament gene promoter in hair follicle cortex, with specificity regulated by additional factors.

This study found that the wavy coat trait in Nakano cataract mice is polygenic, involving major and minor genes, and resembles human curly scalp hair associated with the PRSS53 gene alteration.

ZPK helps skin cells mature and may affect skin health.

Different hair types from various ethnic groups affect hair shine due to characteristics like thickness and shape.

This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.

In this study, researchers reported that hair follicle stem cells maintain quiescence through a PIEZO1-dependent mechanism that senses mechanical forces and translates them into localized calcium influx, involving a transcriptional network that regulates cell adhesion and cytoskeleton-related genes.

This study found that in adult mouse skin, somatosensory axon plasticity is highly dynamic and influenced by epithelial-neural crosstalk and intrinsic neural mechanisms.

In this study, researchers found that the bioactive lipid sphingosine 1-phosphate and its receptor, S1PR3, are essential for regulating mechanical pain sensitivity in mice.

This study suggests that hair-follicle afferent axons can be presynaptically inhibited by boutons containing the enzyme glutamic acid decarboxylase, which is linked to the synthesis of γ-aminobutyric acid.

This study found that subthermal CRET treatment increased keratinocyte proliferation and modulated cytokine production, affecting the inflammatory response in human keratinocytes through EGFR and ERK1/2/NF-κB pathways.

This review discusses the use of contact sensitizers for topical immunotherapy in dermatological conditions such as alopecia areata and viral warts, but it reports no new clinical findings.

In this study, Maas-Szabowski and Szabowski revealed that c-Jun and JunB transcription factors, as well as granulocyte macrophage-colony stimulating factor, regulate human keratinocyte growth and differentiation in fibroblast–keratinocyte interactions.

This study found that Krtap11-1 may play an important role in keratin-bundle assembly in the hair cortex, influencing the physical properties of hair.