Spatiotemporal Dynamics of Sensory Neuron and Merkel-Cell Remodeling During Epidermal Homeostasis

    February 2023 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Rachel C. Clary, Blair A. Jenkins, Ellen A. Lumpkin

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that in adult mouse skin, somatosensory axon plasticity is highly dynamic and influenced by epithelial-neural crosstalk and intrinsic neural mechanisms.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 5

    1. The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development eLife · 2019
    2. Touch Receptors Undergo Rapid Remodeling in Healthy Skin Cell Reports · 2016
    3. Dynamic Plasticity of Axons Within a Cutaneous Milieu Journal of Neuroscience · 2010
    4. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    5. Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin and Hair Growth Modulation by Neuropeptides Journal of Investigative Dermatology · 2001