January 2019 in “Cell & developmental biology” 3D cultivation and prenatal stem cell exosomes improve stem cell treatment results, especially for hair loss and age-related issues.
170 citations,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
6 citations,
September 2009 in “European journal of histochemistry” CD90 is present on specific cells in dog hair follicles.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
9 citations,
February 2014 in “Tissue Engineering and Regenerative Medicine” Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.
291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
1 citations,
April 2021 in “Current Stem Cell Reports” Eating less can improve stem cell function and increase lifespan.
39 citations,
October 2013 in “Plastic and Reconstructive Surgery” Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
12 citations,
May 2019 in “Stem cell reviews” Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.
5 citations,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
35 citations,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
6 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
2 citations,
October 2022 in “Journal of Biomedical Science” Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
17 citations,
June 2017 in “Gene” A rare genetic mutation found in an Indian family can be detected through prenatal screening.
11 citations,
March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
2 citations,
May 2019 in “Advances in wound care” Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
June 2019 in “Stem Cell Research” Scientists created MUSIi010-A, a stem cell line from a balding man's scalp, to study hair loss and develop potential treatments.
66 citations,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
9 citations,
October 2008 in “Mutation research” N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
May 2022 in “Frontiers in Cell and Developmental Biology” miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
7 citations,
July 2014 in “BMJ case reports” A rare skin disorder, Ichthyosis with confetti, has no cure but treatment focuses on managing symptoms with moisturizers.
401 citations,
January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
43 citations,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.