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PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Cannabinoids may help treat various skin conditions.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Araliadiol may promote hair growth like minoxidil without being toxic.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Several new treatments for different types of hair loss show promise in improving patient quality of life.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

Linoleic acid is important for healthy skin and hair.

Recent advances in hair loss treatments show significant progress.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Eating fewer calories may slow skin aging and improve skin health through various biological changes.