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600-630 / 670 resultsresearch Molecular Targeted Agents and Biologic Therapies for Non-Small Cell Lung Cancer
New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
![Biofabrication of Human Skin with Its Appendages](/images/research/007df4db-6df6-4463-9956-90489baac706/small/21352.jpg)
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
![Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One](/images/research/83cefa28-6196-4fa8-b7ac-d02826740e94/small/16903.jpg)
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Deficiency of Crif1 in Hair Follicle Stem Cells Retards Hair Growth Cycle in Adult Mice
Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
![Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease](/images/research/d6c767b0-2c11-43fc-90fe-439ec4838c94/small/19202.jpg)
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Skinny Fat Cells Stimulate Wound Healing
Skinny fat cells help wounds heal faster by releasing fatty acids.
![Frontal Fibrosing Alopecia: A Disease That Remains Enigmatic](/images/research/46455d50-61f0-4c19-b83d-38fdc9311960/small/17536.jpg)
research Frontal Fibrosing Alopecia: A Disease That Remains Enigmatic
Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.
research Expression Profile Analysis of MicroRNAs During Hair Follicle Development in the Sheep Fetus
Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
![Shortcutting the Diagnostic Odyssey: The Multidisciplinary Program for Undiagnosed Rare Diseases in Adults (UD-PrOZA)](/images/research/d02e8bf0-4e70-4dd7-ab59-ec279efd6c13/small/16953.jpg)
research Shortcutting the Diagnostic Odyssey: The Multidisciplinary Program for Undiagnosed Rare Diseases in Adults (UD-PrOZA)
The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.
![Measuring Patient Quality of Life Following Treatment for Alopecia](/images/research/64307f98-390d-40ee-8170-fa8a9c102774/small/15779.jpg)
research Measuring Patient Quality of Life Following Treatment for Alopecia
Alopecia treatments improve life quality but side effects can lessen this benefit; better use of quality of life measures is needed.
research DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research Comparison of the Acute Ultraviolet Photoresponse in Congenic Albino Hairless C57BL/6J Mice Relative to Outbred SKH1 Hairless Mice
B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
![Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza Sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances](/images/research/46acdcf1-d809-420e-a42e-b945da5cc4c8/small/5569.jpg)
research Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza Sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances
Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.
![Consumption of Fish Oil High-Fat Diet Induces Murine Hair Loss via Epidermal Fatty Acid Binding Protein in Skin Macrophages](/images/research/7b47a74b-ad1a-49b3-ae06-81190ad50e8e/small/28490.jpg)
research Consumption of Fish Oil High-Fat Diet Induces Murine Hair Loss via Epidermal Fatty Acid Binding Protein in Skin Macrophages
Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
![Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases](/images/research/f8585f49-0018-46ed-b31a-030666ca0b31/small/16885.jpg)
research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases
EDA signaling is linked to skin disorders, various cancers, and liver disease.
research Safety and Efficacy of ALRV5XR in Women with Androgenetic Alopecia or Telogen Effluvium: A Randomised, Double-Blinded, Placebo-Controlled Clinical Trial
![Role of Regeneration in Tissue Repairing and Therapies](/images/research/4c83778f-2609-43e0-81d7-4fd4c4b030b8/small/19699.jpg)
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
![Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Roles of miRNAs in Sheep Hair Follicle Development](/images/research/bccf00ff-361f-47ce-84f5-7b48d1a89f3b/small/32931.jpg)
research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Roles of miRNAs in Sheep Hair Follicle Development
Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
![Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus Terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis](/images/research/0635591d-065d-4790-b83e-321e67380ebe/small/22809.jpg)
research Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus Terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis
Botryococcus terribilis and its compounds may promote hair growth and improve hair health.
![A Hairy Situation: PADIs in Regeneration and Alopecia](/images/research/89cd9f85-f570-47a9-8423-0ff142768078/small/19218.jpg)
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Graham-Little Piccardi Lassueur Syndrome and Review of the Literature
GLPLS is a rare skin condition with specific hair loss and skin symptoms.
research Orchestration of Tissue-Scale Mechanics and Fate Decisions by Polarity Signaling
Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
research Heat-Killed Enterococcus Faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice
Heat-killed Enterococcus faecalis EF-2001 may promote hair growth and transition hair follicles to the growth phase.
![Analysis of LncRNA-mRNA Co-Expression Profiles in Patients With Polycystic Ovary Syndrome: A Pilot Study](/images/research/ac4a7027-19c5-4f00-a570-1f644acacf10/small/13261.jpg)
research Analysis of LncRNA-mRNA Co-Expression Profiles in Patients With Polycystic Ovary Syndrome: A Pilot Study
Different types of RNAs are found in varying amounts in patients with Polycystic Ovary Syndrome, suggesting they could be important in the disease's development and potentially used as disease markers.
![Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome](/images/research/219b6a2d-d8ec-4f7e-ac9c-8a9bb5438a4d/small/16602.jpg)
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
![Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules](/images/research/35e97991-b167-4def-805d-745851e85df0/small/19193.jpg)
research Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
![Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber](/images/research/f1a9475a-f99b-411c-a230-d2de3eb5d7fa/small/19224.jpg)
research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
Certain genes are linked to the quality of cashmere in goats.
research Safety and Efficacy of ALRV5XR in Men with Androgenetic Alopecia: A Randomised, Double-Blinded, Placebo-Controlled Clinical Trial
![BFNB Enhances Hair Growth in C57BL/6 Mice Through the Induction of EGF and FGF7 Factors and the PI3K-AKT-Beta-Catenin Pathway](/images/research/63a4f6d1-2671-4082-bf81-84938c683cf1/small/16528.jpg)
research BFNB Enhances Hair Growth in C57BL/6 Mice Through the Induction of EGF and FGF7 Factors and the PI3K-AKT-Beta-Catenin Pathway
BFNB could be a promising treatment for hair growth.